Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | HRH2 | P25021 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.39 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9497827 | 0.77 | TYR (0.40) | LMNACHRM1MAPTESR1ADRA1A | |
| SCHEMBL11686897 | 0.75 | TYR (0.39) | LMNACHRM2CHRM1MAPTESR1 | |
| SCHEMBL28278737 | 0.74 | ESR2 (0.49) | MAPTESR1CACNA1CTYRHPGD | |
| SCHEMBL29387138 | 0.74 | CYP2C9 (0.41) | HRH1LMNAHTR2ACHRM2CHRM5 | |
| SCHEMBL211588 | 0.74 | CYP2C9 (0.41) | HRH1LMNAHTR2ACHRM2CHRM5 | |
| SCHEMBL11350007 | 0.73 | GAA (0.35) | LMNACHRM1MAPTESR1ADRA1A | |
| SCHEMBL11352505 | 0.73 | HTR1D (0.33) | LMNAHTR2ACHRM1ESR1ADRA1A | |
| SCHEMBL11353892 | 0.73 | SCN5A (0.33) | LMNACHRM1ESR1ADRA1ASCN5A | |
| SCHEMBL28812642 | 0.71 | TSHR (0.46) | LMNACHRM2CHRM1CHRM3MAPT | |
| SCHEMBL8368366 | 0.70 | TRPA1 (0.40) | HRH1LMNAHTR2ACHRM2CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0496640-B2 | I-ray sensitive positive resist composition | JAPAN SYNTHETIC RUBBER CO LTD (JP) | 2001-09-19 | — | — | EP | disclosed |