Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7866812 | 1.00 | RAB9A (0.47) | RAB9AGAAMAPTNPC1MEN1 | |
| SCHEMBL27818256 | 0.81 | RAB9A (0.49) | RAB9AGAAMAPTNPC1MEN1 | |
| SCHEMBL29951118 | 0.79 | NPSR1 (0.50) | MAPTMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL1060188 | 0.79 | KMT2A (0.49) | RAB9AGAAMAPTMEN1KMT2A | |
| SCHEMBL1060190 | 0.79 | KMT2A (0.49) | RAB9AGAAMAPTMEN1KMT2A | |
| SCHEMBL2248049 | 0.76 | NPSR1 (0.48) | MAPTMEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL29757978 | 0.73 | CYP1A2 (0.48) | MAPTALDH1A1TDP1NPSR1 | |
| SCHEMBL21196844 | 0.73 | CYP1A2 (0.48) | MAPTALDH1A1TDP1NPSR1 | |
| SCHEMBL1810653 | 0.73 | RAB9A (0.47) | RAB9AGAAMAPTNPC1MEN1 | |
| SCHEMBL3985952 | 0.70 | CYP1A1 (0.66) | MAPTMEN1KMT2AALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0741734-B1 | PHENYLBORONIC ACID COMPLEXES | PROLINX INC (US) | 2001-04-04 | — | — | EP | disclosed |
| US-5677431-A | Phenylboronic acid complexes for bioconjugate preparation | PROLINX, INC. (US) | 1997-10-14 | — | — | US | disclosed |
| US-5623055-A | Phenylboronic acid complexes derived from aminosalicylic acid for bioconjugate preparation | PROLINX, INC. (US) | 1997-04-22 | — | — | US | disclosed |
| US-5594111-A | Phenylboronic acid complexes for bioconjugate preparation | PROLINX, INC. (US) | 1997-01-14 | — | — | US | disclosed |
| EP-0741734-A1 | PHENYLBORONIC ACID COMPLEXES | PROLINX, INC. (US) | 1996-11-13 | — | — | EP | disclosed |
| WO-1995020591-A1 | PHENYLBORONIC ACID COMPLEXES | PROLINX, INC. (US) | 1995-08-03 | — | — | WO | disclosed |