Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.45 |
| ▸ | CES2 | O00748 | 2/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 6/20 | 0.41 |
| ▸ | PPARD | Q03181 | 6/20 | 0.41 |
| ▸ | PPARA | Q07869 | 6/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TLR2 | O60603 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | FABP4 | P15090 | 2/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.41 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.41 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7867046 | 1.00 | NAAA (0.45) | NAAACES2HCAR2EPHX1PPARG | |
| SCHEMBL20917519 | 0.91 | ALDH1A1 (0.43) | HCAR2PPARGPPARDPPARAGPR84 | |
| SCHEMBL11240792 | 0.79 | NAAA (0.45) | NAAACES2HCAR2EPHX1PPARG | |
| SCHEMBL20915214 | 0.79 | NAAA (0.45) | NAAACES2HCAR2EPHX1PPARG | |
| SCHEMBL2785037 | 0.79 | NAAA (0.45) | NAAACES2HCAR2EPHX1PPARG | |
| SCHEMBL711761 | 0.79 | NAAA (0.45) | NAAACES2HCAR2EPHX1PPARG | |
| SCHEMBL20936508 | 0.79 | NAAA (0.45) | NAAACES2HCAR2EPHX1PPARG | |
| SCHEMBL20915341 | 0.79 | NAAA (0.45) | NAAACES2HCAR2EPHX1PPARG | |
| SCHEMBL20936457 | 0.79 | NAAA (0.45) | NAAACES2HCAR2EPHX1PPARG | |
| SCHEMBL16497608 | 0.79 | NAAA (0.45) | NAAACES2HCAR2EPHX1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6303740-B1 | INCLUDING STRUCTURES HAVING A HELICAL, TUBULAR OR NEEDLE-LIKE MORPHOLOGY; STRUCTURES MAY BE STABILIZED BY POLYMERIZATION. | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY | 2001-10-16 | — | — | US | claimed |