Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.52 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.52 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20548569 | 0.90 | ALDH1A1 (0.56) | ALDH1A1LMNACYP3A4HSD17B10MAPT | |
| Benzoic Acid SCHEMBL8017354 | 0.86 | PRSS1 (0.63) | ALDH1A1LMNACYP3A4HSD17B10MAPT | |
| SCHEMBL108086 | 0.86 | ALDH1A1 (0.73) | ALDH1A1LMNACYP3A4HSD17B10MAPT | |
| SCHEMBL2822334 | 0.85 | PRSS1 (0.64) | ALDH1A1LMNACYP3A4HSD17B10MAPT | |
| Benzoic Acid SCHEMBL28210602 | 0.85 | PRSS1 (0.58) | ALDH1A1LMNACYP3A4HSD17B10MAPT | |
| SCHEMBL3754816 | 0.84 | ALDH1A1 (0.66) | ALDH1A1LMNACYP3A4HSD17B10MAPT | |
| SCHEMBL2919384 | 0.84 | ALDH1A1 (0.62) | ALDH1A1LMNACYP3A4HSD17B10MAPT | |
| SCHEMBL16968147 | 0.83 | TP53 (0.46) | ALDH1A1LMNAMAPTTSHRTP53 | |
| SCHEMBL571011 | 0.82 | PRSS1 (0.65) | ALDH1A1LMNACYP3A4HSD17B10MAPT | |
| SCHEMBL20924147 | 0.82 | ALDH1A1 (0.77) | ALDH1A1LMNACYP3A4HSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1112314-A1 | FLAME RETARDANT RESIN COMPOSITIONS CONTAINING PHOSPHORAMIDES, AND METHOD FOR MAKING | GENERAL ELECTRIC COMPANY (US) | 2001-07-04 | — | — | EP | disclosed |
| WO-2000012614-A1 | FLAME RETARDANT RESIN COMPOSITIONS CONTAINING PHOSPHORAMIDES, AND METHOD FOR MAKING | GENERAL ELECTRIC COMPANY (US) | 2000-03-09 | — | — | WO | disclosed |
| EP-0427115-A2 | Compatibilized compositions of polyphenylene ether and polyester resins | GENERAL ELECTRIC COMPANY (US) | 1991-05-15 | — | — | EP | disclosed |
| EP-0344099-A2 | A polyester and an article made of the same | SEKISUI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1989-11-29 | — | — | EP | disclosed |