SCHEMBL2822334

SCHEMBL2822334

CCCCCCCCC(CCCCCC)COC(=O)c1ccc(C(=O)OCC(CCCCCC)CCCCCCCC)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRSS1 P07477 1/20 0.64
PRSS2 P07478 1/20 0.64
PRSS3 P35030 1/20 0.64
ALDH1A1 P00352 5/20 0.63
LMNA P02545 4/20 0.63
CYP3A4 P08684 3/20 0.63
HSD17B10 Q99714 1/20 0.63
TSHR P16473 4/20 0.59
MAPK1 P28482 2/20 0.59
CA2 P00918 1/20 0.55
MAPT P10636 2/20 0.54
NPC1 O15118 1/20 0.54
RAB9A P51151 1/20 0.54
CYP1A2 P05177 2/20 0.50
CYP2C19 P33261 2/20 0.50
ESR1 P03372 2/20 0.50
CYP2D6 P10635 1/20 0.50
NR1H2 P55055 1/20 0.50
RNASEL Q05823 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3754816 0.98 ALDH1A1 (0.66) PRSS1PRSS2PRSS3ALDH1A1LMNA
SCHEMBL2919384 0.95 ALDH1A1 (0.62) PRSS1PRSS2PRSS3ALDH1A1LMNA
SCHEMBL3340116 0.94 TSHR (0.60) PRSS1PRSS2PRSS3ALDH1A1LMNA
SCHEMBL3080567 0.94 TSHR (0.60) PRSS1PRSS2PRSS3ALDH1A1LMNA
SCHEMBL9249032 0.94 TSHR (0.60) PRSS1PRSS2PRSS3ALDH1A1LMNA
SCHEMBL21296359 0.94 PRSS1 (0.58) PRSS1PRSS2PRSS3ALDH1A1LMNA
SCHEMBL16694074 0.94 TSHR (0.60) PRSS1PRSS2PRSS3ALDH1A1LMNA
SCHEMBL129099 0.93 ALDH1A1 (0.60) PRSS1PRSS2PRSS3ALDH1A1LMNA
SCHEMBL21296366 0.93 PRSS1 (0.57) PRSS1PRSS2PRSS3ALDH1A1LMNA
SCHEMBL6264048 0.92 PRSS1 (0.68) PRSS1PRSS2PRSS3ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2157159-B1 HYDRAULIC FLUID IDEMITSU KOSAN CO (JP) 2015-12-02 EP disclosed
EP-2674473-A2 Hydraulic fluid and hydraulic system IDEMITSU KOSAN CO., LTD. (JP) 2013-12-18 EP disclosed
US-8299004-B2 Hydraulic fluid and hydraulic system IDEMITSU KOSAN CO., LTD. (JP) 2012-10-30 US disclosed
US-20100130394-A1 HYDRAULIC FLUID AND HYDRAULIC SYSTEM IDEMITSU KOSAN CO., LTD (JP) 2010-05-27 US disclosed
EP-2157159-A1 HYDRAULIC FLUID AND HYDRAULIC SYSTEM Idemitsu Kosan Co., Ltd. (JP) 2010-02-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100130394-A1 HYDRAULIC FLUID AND HYDRAULIC SYSTEM AQP1, AQP3, TECR PRSS1 3532/4885PRSS2 1339/4885PRSS3 3306/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.