⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6076325 | 0.81 | — | — | |
| SCHEMBL21930775 | 0.81 | — | — | |
| SCHEMBL6718031 | 0.81 | — | — | |
| SCHEMBL21930480 | 0.81 | — | — | |
| SCHEMBL6725138 | 0.79 | — | — | |
| SCHEMBL6725143 | 0.79 | — | — | |
| SCHEMBL7865081 | 0.77 | GRIK1 (0.31) | — | |
| SCHEMBL3186126 | 0.76 | ALDH1A1 (0.46) | — | |
| SCHEMBL374306 | 0.76 | ALDH1A1 (0.46) | — | |
| SCHEMBL5061412 | 0.74 | TSHR (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1067122-A2 | Phenylpyrimidine derivatives, process for preparing the same, liquid crystal compositions containing said derivatives as active ingredient, and liquid crystal elements using such compositions | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-01-10 | — | — | EP | disclosed |
| EP-0435632-A2 | Phenylpyrimidine derivatives, process for preparing the same, liquid crystal compositions containing said derivatives as active ingredient, and liquid crystal elements using such compositions | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1991-07-03 | — | — | EP | disclosed |