SCHEMBL374306

SCHEMBL374306

C=CCC(C)CC(=O)OC

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.46
LMNA P02545 1/20 0.46
TSHR P16473 6/20 0.37
HSD17B10 Q99714 1/20 0.34
MGAM O43451 1/20 0.34
GAA P10253 1/20 0.34
SI P14410 1/20 0.34
MGAM2 Q2M2H8 1/20 0.34
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
MAPT P10636 1/20 0.33
RAB9A P51151 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
RECQL P46063 1/20 0.32
POLB P06746 1/20 0.31
POLA1 P09884 1/20 0.31
KCNA5 P22460 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3186126 1.00 ALDH1A1 (0.46) ALDH1A1LMNATSHRHSD17B10MGAM
SCHEMBL29019032 0.90 ALDH1A1 (0.42) ALDH1A1LMNATSHRHSD17B10MGAM
SCHEMBL119899 0.81 TSHR (0.39) ALDH1A1LMNATSHRHSD17B10MGAM
SCHEMBL12820107 0.81 TSHR (0.39) ALDH1A1LMNATSHRHSD17B10MGAM
SCHEMBL27458508 0.80 TSHR (0.49) ALDH1A1LMNATSHRHSD17B10GAA
SCHEMBL10334821 0.80 ALDH1A1 (0.47) ALDH1A1LMNATSHRHSD17B10MGAM
SCHEMBL16154501 0.80 GAA (0.41) ALDH1A1LMNATSHRHSD17B10MGAM
SCHEMBL10334820 0.80 ALDH1A1 (0.47) ALDH1A1LMNATSHRHSD17B10MGAM
SCHEMBL28309630 0.79 LMNA (0.47) ALDH1A1LMNATSHRMAPTRECQL
SCHEMBL265822 0.79 TSHR (0.50) ALDH1A1LMNATSHRHSD17B10MGAM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4076912-A COSMETIC CARRIERS L'OREAL (FR) 1978-02-28 US claimed
US-4070533-A Terpolymer of (a) crotonic acid (b) vinyl acetate and (c) allyl or methallyl esters L'OREAL (FR) 1978-01-24 US claimed
CN-116199806-B Coordination precipitation polymerization method for olefin polymerization and obtained polyolefin 中国石油化工股份有限公司 2025-05-06 CN disclosed
CN-119798492-A Coordination precipitation polymerization process for olefin polymerization and polyolefin 中国石油化工股份有限公司 2025-04-11 CN disclosed
CN-119798493-A Coordination precipitation polymerization process for olefin polymerization and polyolefin 中国石油化工股份有限公司 2025-04-11 CN disclosed
CN-119798491-A Coordination precipitation polymerization process for olefin polymerization and polyolefin 中国石油化工股份有限公司 2025-04-11 CN disclosed
CN-119661749-A Coordination precipitation polymerization process for olefin polymerization and polyolefin 中国石油化工股份有限公司 2025-03-21 CN disclosed
CN-119661750-A Coordination precipitation polymerization process for olefin polymerization and polyolefin 中国石油化工股份有限公司 2025-03-21 CN disclosed
CN-119661751-A Coordination precipitation polymerization process for olefin polymerization and polyolefin 中国石油化工股份有限公司 2025-03-21 CN disclosed
CN-116217759-B Coordination precipitation polymerization method for olefin polymerization and obtained polyolefin 中国石油化工股份有限公司 2025-02-28 CN disclosed
US-20240228680-A1 METHOD FOR PREPARING POLYMER, AND OBTAINED POLYMER CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2024-07-11 US disclosed
US-20070072792-A1 Macrocyclic lactams and pharmaceutical use thereof NOVARTIS AG (CH) 2007-03-29 US disclosed
EP-1682521-A1 MACROCYCLIC LACTAMS AND PHARMACEUTICAL USE THEREOF Novartis AG (CH) 2006-07-26 EP disclosed
WO-2005049585-A1 MACROCYCLIC LACTAMS AND PHARMACEUTICAL USE THEREOF NOVARTIS AG (CH) 2005-06-02 WO disclosed
US-RE29871-E Fatty compositions for use in cosmetic makeup compositions and said cosmetic makeup compositions L'OREAL (FR) 1978-12-26 US disclosed
US-4076912-A COSMETIC CARRIERS L'OREAL (FR) 1978-02-28 US disclosed
US-4070533-A Terpolymer of (a) crotonic acid (b) vinyl acetate and (c) allyl or methallyl esters L'OREAL (FR) 1978-01-24 US disclosed
US-3966404-A CROTONIC ACID-VINYL ACETATE-ALLYL OR METHALLYL ESTER L'OREAL (FR) 1976-06-29 US disclosed
US-3966403-A Hair lacquer or hair setting composition containing a tetrapolymer L'OREAL (FR) 1976-06-29 US disclosed
US-3937811-A COPOLYMER SOCIETE ANONYME DITE: L'OREAL (FR) 1976-02-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070072792-A1 Macrocyclic lactams and pharmaceutical use thereof RPS11, MRPL21, RPS4Y1 ALDH1A1 4236/4885LMNA 1989/4885TSHR 1165/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.