Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13841336 | 0.79 | DAO (0.34) | DAOKDM4C | |
| SCHEMBL3465792 | 0.76 | TAAR1 (0.34) | — | |
| SCHEMBL12000 | 0.74 | — | — | |
| SCHEMBL2038992 | 0.71 | — | — | |
| SCHEMBL14049958 | 0.71 | TYR (0.34) | DAOKDM4C | |
| SCHEMBL8587485 | 0.70 | FDPS (0.41) | DAOKDM4C | |
| SCHEMBL81915 | 0.68 | DAO (0.36) | DAOKDM4C | |
| SCHEMBL10848470 | 0.68 | DAO (0.41) | DAOKDM4C | |
| SCHEMBL132218 | 0.68 | — | — | |
| SCHEMBL9159417 | 0.67 | ALDH1A1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1017687-A4 | PROCESS OF MAKING 3-ARYLOXY, 4-ARYL FURAN-2-ONES USEFUL AS INHIBITORS OF COX-2 | MERCK & CO INC (US) | 2001-10-31 | — | — | EP | disclosed |
| US-6140515-A | Process of making 3-aryloxy, 4-aryl furan-2-ones useful as inhibitors of COX-2 | MERCK & CO., INC. (US) | 2000-10-31 | — | — | US | disclosed |
| EP-1017687-A1 | PROCESS OF MAKING 3-ARYLOXY, 4-ARYL FURAN-2-ONES USEFUL AS INHIBITORS OF COX-2 | Merck & Co., Inc. (US) | 2000-07-12 | — | — | EP | disclosed |
| WO-1999015513-A1 | PROCESS OF MAKING 3-ARYLOXY, 4-ARYL FURAN-2-ONES USEFUL AS INHIBITORS OF COX-2 | MERCK & CO., INC. (US) | 1999-04-01 | — | — | WO | disclosed |