SCHEMBL7867607

SCHEMBL7867607

CCCc1cc(C)c(O)cc1C(C)(C)C

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 6/20 0.45
ALDH1A1 P00352 5/20 0.45
SMN1; SMN2 Q16637 4/20 0.45
CYP1A2 P05177 3/20 0.45
KDM4E B2RXH2 2/20 0.45
MAPT P10636 2/20 0.45
ATP2A2 P16615 1/20 0.45
ATP2A3 Q93084 1/20 0.45
CYP2C9 P11712 6/20 0.42
CYP2C19 P33261 5/20 0.42
TP53 P04637 3/20 0.42
CYP2D6 P10635 3/20 0.42
ESR1 P03372 5/20 0.38
HIF1A Q16665 4/20 0.38
ESR2 Q92731 3/20 0.38
CYP3A4 P08684 3/20 0.38
AR P10275 2/20 0.38
HSPA5 P11021 2/20 0.38
MAPK1 P28482 2/20 0.38
HMGCR P04035 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18272012 0.93 CYP2C9 (0.42) ALOX15ALDH1A1SMN1; SMN2CYP1A2KDM4E
SCHEMBL5181980 0.89 TYR (0.43) ALOX15ALDH1A1SMN1; SMN2CYP1A2KDM4E
SCHEMBL9142981 0.86 ALOX5 (0.46) ALOX15ALDH1A1SMN1; SMN2CYP1A2KDM4E
SCHEMBL11795839 0.85 ALOX15 (0.45) ALOX15ALDH1A1SMN1; SMN2CYP1A2KDM4E
SCHEMBL27482806 0.85 HMGCR (0.46) ALOX15ALDH1A1SMN1; SMN2CYP1A2KDM4E
SCHEMBL9154600 0.82 ALOX15 (0.50) ALOX15ALDH1A1SMN1; SMN2CYP1A2KDM4E
SCHEMBL23387419 0.80 HMGCR (0.45) ALOX15ALDH1A1CYP1A2KDM4EMAPT
SCHEMBL6659557 0.80 NPSR1 (0.58) ALOX15ALDH1A1SMN1; SMN2CYP1A2KDM4E
SCHEMBL29359286 0.80 NPSR1 (0.58) ALOX15ALDH1A1SMN1; SMN2CYP1A2KDM4E
SCHEMBL27435373 0.79 ALOX15 (0.42) ALOX15ALDH1A1SMN1; SMN2CYP1A2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116736653-A Electrophotographic photoreceptor, process cartridge, and image forming apparatus 富士胶片商业创新有限公司 2023-09-12 CN disclosed
CN-107844036-B Electrophotographic photoreceptor, process cartridge, and image forming apparatus 富士胶片商业创新有限公司 2022-08-30 CN disclosed
CN-105867079-B Electrophotographic photoreceptor, process cartridge, and image forming apparatus 富士施乐株式会社 2019-12-17 CN disclosed
CN-101472995-B Polycarbonate compositions and articles formed therefrom SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2011-12-28 CN disclosed
CN-101472995-A Polycarbonate compositions and articles formed therefrom GEN ELECTRIC (NL) 2009-07-01 CN disclosed
CN-101472994-A Polycarbonate compositions and articles formed therefrom GEN ELECTRIC (NL) 2009-07-01 CN disclosed
CN-101400763-A Halogen-free polycarbonate compositions and articles formed therefrom SABIC INNOVATIVE PLASTICS IP (NL) 2009-04-01 CN disclosed
CN-101384684-A Polycarbonate compositions and articles formed therefrom GEN ELECTRIC (US) 2009-03-11 CN disclosed
CN-101379114-A Thermally stable polycarbonates, thermoplastic compositions thereof, and articles made therefrom GEN ELECTRIC (US) 2009-03-04 CN disclosed
CN-101356235-A Polycarbonate compositions and articles formed therefrom, with matte surfaces and high light transmissions GEN ELECTRIC (US) 2009-01-28 CN disclosed
CN-1383450-A Antibody molecule with specificity to human tumor necrosis factor alpha and application thereof CELLTECH R&D LTD (GB) 2002-12-04 CN disclosed
EP-1069146-A1 POLYCARBONATE AND OPTICAL MATERIAL Idemitsu Petrochemical Co., Ltd. (JP) 2001-01-17 EP disclosed
EP-0411192-B1 Electrophotographic photoreceptor IDEMITSU KOSAN CO (JP) 1995-06-07 EP disclosed
US-5389444-A Polycarbonate containing styrylamine repeating unit and emitter, and hole injecting material IDEMITSU KOSAN CO., LTD. (JP) 1995-02-14 US disclosed
EP-0557534-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN COMPANY LIMITED (JP) 1993-09-01 EP disclosed
EP-0411192-A1 Electrophotographic photoreceptor IDEMITSU KOSAN COMPANY LIMITED (JP) 1991-02-06 EP disclosed