SCHEMBL7867628

SCHEMBL7867628

COc1cnc(OC)n2nc(NS(=O)(=O)c3ccccc3)nc12

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC40A1 Q9NP59 2/20 0.45
SMN1; SMN2 Q16637 3/20 0.44
TSHR P16473 3/20 0.44
CCR4 P51679 1/20 0.43
GLA P06280 1/20 0.43
NPSR1 Q6W5P4 1/20 0.42
MCOLN2 Q8IZK6 1/20 0.42
MCOLN3 Q8TDD5 1/20 0.42
MCOLN1 Q9GZU1 1/20 0.42
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
LMNA P02545 3/20 0.41
MAPT P10636 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
KDM1A O60341 1/20 0.41
ALDH1A1 P00352 2/20 0.40
KDM4E B2RXH2 1/20 0.40
CYP17A1 P05093 2/20 0.40
HTR6 P50406 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7859430 0.86 KAT7 (0.38) SLC40A1LMNATDP1ALDH1A1
SCHEMBL7236520 0.81 CCR4 (0.35) CCR4MEN1KMT2ALMNAALDH1A1
SCHEMBL7859400 0.80 ALPL (0.50) SMN1; SMN2TSHRNPSR1MEN1KMT2A
SCHEMBL6630344 0.79 CCR4 (0.37) SLC40A1CCR4KMT2AMAPT
SCHEMBL7860914 0.78 SLC22A12 (0.35) CCR4NPSR1MEN1KMT2AALDH1A1
SCHEMBL16359710 0.78 SLC22A12 (0.41) SLC40A1TSHRCCR4KMT2A
SCHEMBL7870583 0.77 ALPL (0.44) SLC40A1
SCHEMBL7859410 0.76 CCR4 (0.39) CCR4MEN1KMT2AALDH1A1
SCHEMBL4394420 0.76 SLC22A12 (0.39) TSHRCCR4
SCHEMBL15449646 0.76 EDNRA (0.35) SMN1; SMN2CYP17A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0877745-B1 N-( 1,2,4] TRIAZOLOAZINYL)BENZENESULFONAMIDE AND PYRIDINESULFONAMIDE COMPOUNDS AND THEIR USE AS HERBICIDES DOW AGROSCIENCES LLC (US) 2001-07-25 EP claimed