Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 9/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 11/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1264473 | 0.84 | ACHE (0.60) | ACHE | |
| SCHEMBL1264493 | 0.81 | ACHE (0.58) | ACHEHDAC6HDAC11 | |
| SCHEMBL1262984 | 0.68 | ACHE (0.54) | ACHE | |
| SCHEMBL1264152 | 0.66 | ACHE (0.51) | ACHEHDAC6 | |
| SCHEMBL1263029 | 0.65 | HDAC6 (0.48) | HDAC6HDAC11HDAC8 | |
| SCHEMBL612135 | 0.63 | ALDH1A1 (0.63) | HDAC6HDAC8 | |
| SCHEMBL368469 | 0.63 | HDAC6 (0.59) | HDAC6HDAC8 | |
| SCHEMBL10120352 | 0.63 | HDAC6 (0.57) | HDAC6HDAC8 | |
| SCHEMBL10120351 | 0.63 | HDAC6 (0.57) | HDAC6HDAC8 | |
| SCHEMBL1174394 | 0.63 | ACHE (0.53) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010151318-A1 | SUBSTITUTED HYDROXAMIC ACIDS AND USES THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2010-12-29 | — | — | WO | disclosed |