Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR3 | O15455 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CFTR | P13569 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MGAM | O43451 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3456479 | 0.79 | MEN1 (0.51) | TLR3MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL10509687 | 0.77 | TLR3 (0.45) | TLR3MEN1KMT2ACNR1CNR2 | |
| SCHEMBL9091707 | 0.73 | TLR3 (0.43) | TLR3MEN1KMT2ATRPV1CNR1 | |
| SCHEMBL13090968 | 0.71 | KMT2A (0.46) | TLR3MEN1KMT2ATRPV1CNR1 | |
| SCHEMBL11037376 | 0.71 | KDM4E (0.46) | TLR3MEN1KMT2ACNR1CNR2 | |
| SCHEMBL7608955 | 0.71 | MAPT (0.46) | TLR3MEN1KMT2ACNR1CNR2 | |
| SCHEMBL3318159 | 0.70 | CFTR (0.46) | TLR3TRPV1CFTRAKR1B1 | |
| SCHEMBL3319434 | 0.70 | KCNE1 (0.44) | TLR3MEN1KMT2ATRPV1CFTR | |
| SCHEMBL31085042 | 0.70 | TRPV1 (0.43) | TLR3MEN1KMT2ATRPV1CNR1 | |
| SCHEMBL3318162 | 0.70 | CFTR (0.46) | TLR3TRPV1CFTRAKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0571822-B1 | Diazabicycloalkene derivatives | DAIICHI SEIYAKU CO (JP) | 2001-08-16 | — | — | EP | disclosed |
| US-5418232-A | Hypotensive, increases renal blood flow | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1995-05-23 | — | — | US | disclosed |
| EP-0571822-A1 | Diazabicycloalkene derivatives | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1993-12-01 | — | — | EP | disclosed |