Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | FLT4 | P35916 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CCNE2 | O96020 | 4/20 | 0.36 |
| ▸ | CCNE1 | P24864 | 4/20 | 0.36 |
| ▸ | CDK2 | P24941 | 4/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7867772 | 0.83 | HSP90AA1 (0.38) | FLT4KDRCCNE2CCNE1CDK2 | |
| SCHEMBL7872825 | 0.81 | FLT4 (0.47) | PTGS2FLT4KDRHPGD | |
| SCHEMBL9584054 | 0.75 | MEN1 (0.39) | CCNE2CCNE1CDK2HPGDKMT2A | |
| SCHEMBL9583267 | 0.75 | MEN1 (0.39) | FLT4KDRCCNE2CCNE1CDK2 | |
| SCHEMBL9583487 | 0.75 | KMT2A (0.35) | CCNE2CCNE1CDK2HPGDKMT2A | |
| SCHEMBL9584080 | 0.75 | KMT2A (0.35) | FLT4KDRCCNE2CCNE1CDK2 | |
| SCHEMBL9583529 | 0.75 | MEN1 (0.39) | CCNE2CCNE1CDK2HPGDKMT2A | |
| SCHEMBL9583068 | 0.74 | HSP90AA1 (0.35) | CCNE2CCNE1CDK2HPGDKMT2A | |
| SCHEMBL9584856 | 0.74 | PDE3A (0.33) | RAB9ACCNE2CCNE1CDK2KMT2A | |
| SCHEMBL7872971 | 0.74 | FLT4 (0.45) | FLT4KDRHPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6316595-B1 | PNA synthesis using a base-labile amino protecting group | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2001-11-13 | — | — | US | disclosed |
| US-6121418-A | PNA synthesis using a base-labile amino protecting group | HOECHST AKTIENGESELLSCHAFT (DE) | 2000-09-19 | — | — | US | disclosed |