Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT4 | P35916 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7872825 | 0.92 | FLT4 (0.47) | FLT4KDRHPGDEGFRTAAR1 | |
| SCHEMBL9583392 | 0.82 | HPGD (0.42) | FLT4KDRHPGDKMT2ATAAR1 | |
| SCHEMBL9584577 | 0.82 | HPGD (0.38) | FLT4KDRHPGDKMT2ATAAR1 | |
| SCHEMBL7878996 | 0.81 | FLT4 (0.34) | FLT4KDRHPGDTAAR1 | |
| SCHEMBL7867772 | 0.81 | HSP90AA1 (0.38) | FLT4KDRHPGDKMT2A | |
| SCHEMBL7879002 | 0.78 | DOT1L (0.34) | FLT4KDRHPGDKMT2ATP53 | |
| SCHEMBL9583154 | 0.78 | HPGD (0.35) | FLT4KDRHPGDTP53 | |
| SCHEMBL8150607 | 0.76 | KMT2A (0.36) | FLT4KDRHPGDKMT2ATP53 | |
| SCHEMBL9583074 | 0.76 | HPGD (0.36) | FLT4KDRHPGDEGFRTAAR1 | |
| SCHEMBL7872974 | 0.73 | HDAC1 (0.47) | FLT4KDRHPGDEGFRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6316595-B1 | PNA synthesis using a base-labile amino protecting group | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2001-11-13 | — | — | US | disclosed |
| US-6121418-A | PNA synthesis using a base-labile amino protecting group | HOECHST AKTIENGESELLSCHAFT (DE) | 2000-09-19 | — | — | US | disclosed |