Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT4 | P35916 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 2/20 | 0.40 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7872971 | 0.92 | FLT4 (0.45) | FLT4KDRHPGDEGFRNSD3 | |
| SCHEMBL9583392 | 0.84 | HPGD (0.42) | FLT4KDRHPGDNSD3TP53 | |
| SCHEMBL9584577 | 0.83 | HPGD (0.38) | FLT4KDRHPGDNSD3TP53 | |
| SCHEMBL7867928 | 0.81 | PTGS2 (0.41) | FLT4KDRHPGDPTGS2 | |
| SCHEMBL9583154 | 0.78 | HPGD (0.35) | FLT4KDRHPGDTP53 | |
| SCHEMBL7878996 | 0.78 | FLT4 (0.34) | FLT4KDRHPGDTAAR1ADORA2A | |
| SCHEMBL8150607 | 0.77 | KMT2A (0.36) | FLT4KDRHPGDTP53 | |
| SCHEMBL9583074 | 0.77 | HPGD (0.36) | FLT4KDRHPGDEGFRNSD3 | |
| SCHEMBL7879002 | 0.75 | DOT1L (0.34) | FLT4KDRHPGDTP53 | |
| SCHEMBL30089853 | 0.73 | FLT4 (0.43) | FLT4KDREGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6316595-B1 | PNA synthesis using a base-labile amino protecting group | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2001-11-13 | — | — | US | disclosed |
| US-6121418-A | PNA synthesis using a base-labile amino protecting group | HOECHST AKTIENGESELLSCHAFT (DE) | 2000-09-19 | — | — | US | disclosed |