SCHEMBL7868042

SCHEMBL7868042

CC(Cl)(Cl)C(Cl)(Cl)C(=O)O

nearest known ligand 0.47

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.47
ALDH1A1 P00352 2/20 0.47
TP53 P04637 1/20 0.47
CYP2D6 P10635 1/20 0.35
CYP2C19 P33261 1/20 0.35
HIF1A Q16665 1/20 0.35
THRB P10828 1/20 0.32
CYP1A2 P05177 1/20 0.31
HMGCR P04035 1/20 0.30
CHRM1 P11229 1/20 0.30
TBXA2R P21731 1/20 0.30
ADRA1A P35348 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11401734 0.81 TSHR (0.42) TSHRALDH1A1TP53CYP2D6CYP2C19
SCHEMBL10496056 0.80 TSHR (0.47) TSHRALDH1A1TP53CYP2D6CYP2C19
SCHEMBL5610973 0.78 TSHR (0.61) TSHRALDH1A1TP53CYP1A2
SCHEMBL9848546 0.78 TSHR (0.44) TSHRALDH1A1TP53CYP2D6CYP2C19
SCHEMBL29002148 0.74 ALDH1A1 (0.57) TSHRALDH1A1TP53CYP1A2
Dalapon SCHEMBL4895986 0.74 TSHR (0.57) TSHRALDH1A1TP53CYP2D6CYP2C19
SCHEMBL301323 0.74
SCHEMBL1678472 0.74 TSHR (0.57) TSHRALDH1A1TP53CYP2D6CYP2C19
Dalapon SCHEMBL45164 0.74
SCHEMBL11377732 0.73 TSHR (0.32) TSHRALDH1A1TP53THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1124786-A1 PROCESS FOR THE PREPARATION AND USES OF DERIVATIVES OF ESTERS OF ALPHA-METHYLENE- BETA-HYDROXY ACIDS Uniroyal Chemical Company, Inc. (US) 2001-08-22 EP claimed
WO-2000027793-A1 PROCESS FOR THE PREPARATION AND USES OF DERIVATIVES OF ESTERS OF ALPHA- METHYLENE- BETA- HYDROXY ACIDS UNIROYAL CHEMICAL COMPANY, INC. (US) 2000-05-18 WO claimed
CN-1104194-C Granular agrochemical formulations SANKYO CO (JP) 2003-04-02 CN disclosed
EP-1124786-A1 PROCESS FOR THE PREPARATION AND USES OF DERIVATIVES OF ESTERS OF ALPHA-METHYLENE- BETA-HYDROXY ACIDS Uniroyal Chemical Company, Inc. (US) 2001-08-22 EP disclosed
WO-2000027793-A1 PROCESS FOR THE PREPARATION AND USES OF DERIVATIVES OF ESTERS OF ALPHA- METHYLENE- BETA- HYDROXY ACIDS UNIROYAL CHEMICAL COMPANY, INC. (US) 2000-05-18 WO disclosed
CN-1123082-A Granular agrochemical formulations SANKYO CO (JP) 1996-05-29 CN disclosed
US-4265931-A NONMAGNETIC SUPPORTS CONTAINING A THERMOSETTING BINDER FUJI PHOTO FILM CO., LTD. (JP) 1981-05-05 US disclosed