Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 4/20 | 0.49 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | XDH | P47989 | 1/20 | 0.38 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL77894 | 0.87 | KDM4E (0.44) | AOC3ALDH1A1HPGDKDM4EHSD17B10 | |
| Hydrazine SCHEMBL14688080 | 0.84 | KDM4E (0.43) | AOC3ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL6183673 | 0.82 | AOC3 (0.45) | AOC3KDM4CALDH1A1MAPK1HPGD | |
| Hydrochloric Acid SCHEMBL7817921 | 0.81 | AOC3 (0.44) | AOC3KDM4CALDH1A1MAPK1HPGD | |
| SCHEMBL27568977 | 0.80 | GABRP (0.39) | ALDH1A1MAPK1CYP1A2KDM4ETDP1 | |
| SCHEMBL2427291 | 0.78 | ALDH1A1 (0.44) | AOC3KDM4CALDH1A1MAPK1HPGD | |
| SCHEMBL9349416 | 0.78 | ALDH1A1 (0.47) | AOC3KDM4CALDH1A1MAPK1CYP1A2 | |
| SCHEMBL9786032 | 0.77 | AOC3 (0.42) | AOC3ALDH1A1MAPK1KDM4EHSD17B10 | |
| Hydrochloric Acid SCHEMBL6182013 | 0.77 | ALDH1A1 (0.43) | AOC3KDM4CALDH1A1MAPK1HPGD | |
| SCHEMBL768427 | 0.76 | AOC3 (0.63) | AOC3KDM4CALDH1A1MAPK1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0729953-A2 | A process for producing a 2-substituted-3,4-fused heterocyclic benzoic acid | ROHM AND HAAS COMPANY (US) | 1996-09-04 | — | — | EP | claimed |
| EP-0602794-A2 | Insecticidal N'-substituted-N, N'-diacylhydrazines | ROHM AND HAAS COMPANY (US) | 1994-06-22 | — | — | EP | claimed |
| EP-0729934-A2 | A process for producing a 3-alkoxy-2-(substituted)benzoic acid or an ester thereof | ROHM AND HAAS COMPANY (US) | 1996-09-04 | — | — | EP | disclosed |
| EP-0729953-A2 | A process for producing a 2-substituted-3,4-fused heterocyclic benzoic acid | ROHM AND HAAS COMPANY (US) | 1996-09-04 | — | — | EP | disclosed |
| EP-0602794-A2 | Insecticidal N'-substituted-N, N'-diacylhydrazines | ROHM AND HAAS COMPANY (US) | 1994-06-22 | — | — | EP | disclosed |
| US-4910206-A | Endotoxin induced lung injury | SANDOZ PHARMACEUTICALS CORP. (US) | 1990-03-20 | — | — | US | disclosed |
| US-4140859-A | Dilithiated 2-(o-tolyl)-2-imidazolines | SANDOZ, INC. (US) | 1979-02-20 | — | — | US | disclosed |
| US-4101553-A | Imidazo[2,1-a]isoquinolines | SANDOZ, INC. (US) | 1978-07-18 | — | — | US | disclosed |