Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.51 |
| ▸ | GRM5 | P41594 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7861475 | 0.89 | ALDH1A1 (0.50) | CYP1A2CYP2C9CYP2C19ALDH1A1GRM5 | |
| SCHEMBL7869776 | 0.88 | ALDH1A1 (0.47) | CYP1A2CYP2C9CYP2C19ALDH1A1GRM5 | |
| SCHEMBL7873004 | 0.86 | GRM5 (0.56) | CYP1A2CYP2C9CYP2C19ALDH1A1GRM5 | |
| SCHEMBL7872821 | 0.84 | SMN1; SMN2 (0.43) | ALDH1A1GRM5LMNAMAPTL3MBTL1 | |
| SCHEMBL7861522 | 0.83 | ADRA2A (0.49) | ALDH1A1GRM5LMNAMAPTL3MBTL1 | |
| SCHEMBL7869768 | 0.81 | PARP1 (0.46) | ALDH1A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL7866466 | 0.80 | TTK (0.42) | ALDH1A1LMNAMAPTL3MBTL1HSD11B1 | |
| SCHEMBL8711943 | 0.79 | CYP1A2 (0.55) | CYP1A2CYP2C9CYP2C19ALDH1A1GRM5 | |
| SCHEMBL7869046 | 0.76 | ADRA2A (0.46) | ALDH1A1LMNAMAPTL3MBTL1HSD11B1 | |
| SCHEMBL7866495 | 0.76 | ADRA2A (0.46) | ALDH1A1HSD11B1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6306860-B1 | ANTIVIRAL ACTIVITIES AGAINST HEPATATIS B AS WELL AS HUMAN IMMUNODEFICIENCY VIRUS | DONG WHA PHARM. INC. CO., LTD. (KR) | 2001-10-23 | — | — | US | disclosed |
| WO-1999058526-A1 | NOVEL 2,5-PYRIDINEDICARBOXYLIC ACID DERIVATIVES | DONG WHA PHARM. IND. CO., LTD. (KR) | 1999-11-18 | — | — | WO | disclosed |