SCHEMBL7868209

SCHEMBL7868209

CCCCCCN[C@]1(n2cnc3c(N)ncnc32)C[C@H](O)[C@@H](CO)O1

nearest known ligand 0.47

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
SLC28A1 O00337 1/20 0.47
ADORA2A P29274 2/20 0.45
ADORA3 P0DMS8 1/20 0.45
ALDH1A1 P00352 1/20 0.45
EHMT1 Q9H9B1 1/20 0.43
PI4KA P42356 1/20 0.41
PI4K2B Q8TCG2 1/20 0.41
PI4K2A Q9BTU6 1/20 0.41
PI4KB Q9UBF8 1/20 0.41
GMPS P49915 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7610242 0.81 EHMT1 (0.46) SLC28A1ADORA2AADORA3ALDH1A1EHMT1
SCHEMBL5168015 0.81 SLC28A1 (0.50) SLC28A1ADORA2AADORA3EHMT1PI4KA
SCHEMBL10439450 0.81 SLC28A1 (0.50) SLC28A1ADORA2AADORA3PI4KAPI4K2B
SCHEMBL9120616 0.79 SLC28A1 (0.49) SLC28A1ADORA2AADORA3EHMT1PI4KA
SCHEMBL6756465 0.78 SLC28A1 (0.57) SLC28A1ADORA2AADORA3PI4KAPI4K2B
SCHEMBL29362292 0.78 SLC28A1 (0.57) SLC28A1ADORA2AADORA3PI4KAPI4K2B
SCHEMBL25222252 0.78 SLC28A1 (0.54) SLC28A1ADORA2AADORA3PI4KAPI4K2B
SCHEMBL29786250 0.78 SLC28A1 (0.54) SLC28A1ADORA2AADORA3PI4KAPI4K2B
SCHEMBL1900941 0.77 AHCY (0.46) SLC28A1ADORA2AADORA3EHMT1PI4KA
SCHEMBL439243 0.77 SLC28A1 (0.56) SLC28A1ADORA2AADORA3PI4KAPI4K2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1090137-A1 PRODUCTION OF POLYMERS FROM NUCLEOTIDIC AND/OR NON-NUCLEOTIDIC ELEMENTS USING ENZYMATIC METHODS Larova Biochemie GmbH (DE) 2001-04-11 EP disclosed
WO-1999067413-A1 PRODUCTION OF POLYMERS FROM NUCLEOTIDIC AND/OR NON-NUCLEOTIDIC ELEMENTS USING ENZYMATIC METHODS LAROVA BIOCHEMIE GMBH (DE) 1999-12-29 WO disclosed