Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.46 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | CD4 | P01730 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7866689 | 0.87 | HDAC6 (0.49) | MAPTSMN1; SMN2TP53LMNAGAA | |
| SCHEMBL1264363 | 0.84 | PKM (0.57) | MAPTSMN1; SMN2TP53PKMLMNA | |
| SCHEMBL12895917 | 0.83 | HDAC6 (0.56) | MAPTSMN1; SMN2PKMLMNAGAA | |
| SCHEMBL1263013 | 0.76 | PKM (0.51) | MAPTSMN1; SMN2TP53PKMLMNA | |
| SCHEMBL12895926 | 0.76 | LMNA (0.47) | MAPTSMN1; SMN2TP53PKMLMNA | |
| SCHEMBL1264273 | 0.75 | HDAC6 (0.50) | MAPTSMN1; SMN2TP53PKMLMNA | |
| SCHEMBL1263154 | 0.75 | HDAC1 (0.51) | MAPTSMN1; SMN2TP53PKMLMNA | |
| SCHEMBL16975880 | 0.74 | HDAC6 (0.52) | MAPTSMN1; SMN2TP53LMNAHDAC6 | |
| SCHEMBL1263174 | 0.73 | HDAC6 (0.70) | MAPTSMN1; SMN2TP53PKMLMNA | |
| SCHEMBL1263325 | 0.72 | MAPT (0.49) | MAPTTP53GAAHDAC6SMPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010151318-A1 | SUBSTITUTED HYDROXAMIC ACIDS AND USES THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2010-12-29 | — | — | WO | disclosed |