Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.77 |
| ▸ | POLB | P06746 | 1/20 | 0.67 |
| ▸ | CA12 | O43570 | 1/20 | 0.58 |
| ▸ | CA1 | P00915 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.58 |
| ▸ | CA5A | P35218 | 1/20 | 0.58 |
| ▸ | CA9 | Q16790 | 1/20 | 0.58 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | PPARG | P37231 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.53 |
| ▸ | SGMS1 | Q86VZ5 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29260159 | 0.90 | ALDH1A1 (0.81) | ALDH1A1SMN1; SMN2POLBCA12CA1 | |
| SCHEMBL7113122 | 0.88 | ALDH1A1 (1.00) | ALDH1A1SMN1; SMN2POLBCA12CA1 | |
| SCHEMBL7877032 | 0.84 | ALDH1A1 (0.60) | ALDH1A1SMN1; SMN2POLBCA12CA1 | |
| SCHEMBL10589292 | 0.84 | ALDH1A1 (0.86) | ALDH1A1SMN1; SMN2POLBCA12CA1 | |
| SCHEMBL10523408 | 0.84 | ALDH1A1 (0.86) | ALDH1A1SMN1; SMN2POLBCA12CA1 | |
| SCHEMBL6799293 | 0.84 | ALDH1A1 (0.86) | ALDH1A1SMN1; SMN2POLBCA12CA1 | |
| SCHEMBL7879606 | 0.84 | ALDH1A1 (0.65) | ALDH1A1SMN1; SMN2POLBCA1CA2 | |
| SCHEMBL15619063 | 0.82 | ALDH1A1 (0.88) | ALDH1A1SMN1; SMN2POLBCA12CA1 | |
| SCHEMBL11335294 | 0.82 | ALDH1A1 (0.88) | ALDH1A1SMN1; SMN2POLBCA12CA1 | |
| SCHEMBL29259801 | 0.81 | ALDH1A1 (1.00) | ALDH1A1SMN1; SMN2POLBCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6326500-B1 | ANTIINFLAMMATORY AGENTS; ANTIALLERGENS | ABBOTT LABORATORIES | 2001-12-04 | — | — | US | disclosed |
| US-6215001-B1 | ANTIINFLAMMATORY AGENTS, ANTIASTHMATICS, AND ANTIALLERGENS; SIDE EFFECT REDUCTION | KNOLL AKTIENGESELLSCHAFT (DE) | 2001-04-10 | — | — | US | disclosed |
| US-6031109-A | Phenoxy-, phenylthio-, benzoyl-alkyleneaminoalkylene-imidazole derivatives as therapeutic agents | KNOLL AKTIENGESELLSCHAFT (DE) | 2000-02-29 | — | — | US | disclosed |
| EP-0705251-A1 | IMIDAZOLE DERIVATIVES AS THERAPEUTIC AGENTS | Knoll AG (DE) | 1996-04-10 | — | — | EP | disclosed |
| WO-1995000493-A1 | IMIDAZOLE DERIVATIVES AS THERAPEUTIC AGENTS | KNOLL AG (DE) | 1995-01-05 | — | — | WO | disclosed |