Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | HTT | P42858 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | CA5A | P35218 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | PDE4A | P27815 | 1/20 | 0.54 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.54 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.54 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.54 |
| ▸ | SFRP1 | Q8N474 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7868628 | 0.84 | ALDH1A1 (0.77) | ALDH1A1HTTSMN1; SMN2POLBKMT2A | |
| SCHEMBL7416728 | 0.82 | HTT (0.76) | ALDH1A1HTTSMN1; SMN2POLBKMT2A | |
| SCHEMBL10453025 | 0.80 | PDE4A (0.66) | ALDH1A1HTTSMN1; SMN2POLBKMT2A | |
| SCHEMBL7877042 | 0.80 | PDE4A (0.65) | ALDH1A1HTTSMN1; SMN2POLBKMT2A | |
| SCHEMBL4182162 | 0.79 | KMT2A (0.77) | ALDH1A1HTTSMN1; SMN2POLBKMT2A | |
| SCHEMBL7879606 | 0.78 | ALDH1A1 (0.65) | ALDH1A1HTTSMN1; SMN2POLBKMT2A | |
| SCHEMBL10462165 | 0.78 | TBXA2R (0.63) | ALDH1A1HTTSMN1; SMN2POLBKMT2A | |
| SCHEMBL15618874 | 0.77 | ALDH1A1 (0.72) | ALDH1A1HTTSMN1; SMN2POLBCA12 | |
| SCHEMBL5960103 | 0.76 | ALDH1A1 (0.79) | ALDH1A1HTTSMN1; SMN2POLBKMT2A | |
| SCHEMBL7879458 | 0.76 | LSS (0.62) | ALDH1A1HTTSMN1; SMN2KMT2ACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6326500-B1 | ANTIINFLAMMATORY AGENTS; ANTIALLERGENS | ABBOTT LABORATORIES | 2001-12-04 | — | — | US | disclosed |
| US-6215001-B1 | ANTIINFLAMMATORY AGENTS, ANTIASTHMATICS, AND ANTIALLERGENS; SIDE EFFECT REDUCTION | KNOLL AKTIENGESELLSCHAFT (DE) | 2001-04-10 | — | — | US | disclosed |
| US-6031109-A | Phenoxy-, phenylthio-, benzoyl-alkyleneaminoalkylene-imidazole derivatives as therapeutic agents | KNOLL AKTIENGESELLSCHAFT (DE) | 2000-02-29 | — | — | US | disclosed |
| WO-1995000493-A1 | IMIDAZOLE DERIVATIVES AS THERAPEUTIC AGENTS | KNOLL AG (DE) | 1995-01-05 | — | — | WO | disclosed |