SCHEMBL786864

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL772171	0.98	EPHX2 (0.58)	EPHX2HTTALOX5MEN1KMT2A
	SCHEMBL772544	0.93	EPHX1 (0.51)	EPHX2HTTALOX5MEN1KMT2A
	SCHEMBL770872	0.90	EPHX2 (0.53)	EPHX2MEN1KMT2AEPHX1
	SCHEMBL12986920	0.90	EPHX2 (0.45)	EPHX2HTTALOX5MEN1KMT2A
	SCHEMBL769863	0.88	EPHX2 (0.56)	EPHX2ALOX5MEN1KMT2AEPHX1
	SCHEMBL769951	0.88	EPHX2 (0.56)	EPHX2HTTALOX5MEN1KMT2A
	SCHEMBL770614	0.86	HDAC3 (0.50)	EPHX2MEN1KMT2AEPHX1HDAC3
	SCHEMBL771370	0.85	HDAC3 (0.49)	EPHX2MEN1KMT2AEPHX1HDAC3
	SCHEMBL770472	0.83	EPHX2 (0.51)	EPHX2EPHX1TSHR
	SCHEMBL771381	0.82	GBA1 (0.47)	EPHX2MEN1KMT2AHDAC3HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.