Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17243236 | 1.00 | TLR4 (0.47) | TLR4GAATDP1L3MBTL1ALDH1A1 | |
| SCHEMBL19710403 | 0.93 | GAA (0.48) | TLR4GAATDP1L3MBTL1ALDH1A1 | |
| SCHEMBL5954267 | 0.89 | TLR4 (0.45) | TLR4ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL1242931 | 0.86 | NPC1 (0.52) | GAATDP1L3MBTL1ALDH1A1LMNA | |
| SCHEMBL11439257 | 0.86 | NPC1 (0.52) | GAATDP1L3MBTL1ALDH1A1LMNA | |
| SCHEMBL28004812 | 0.86 | NPC1 (0.52) | GAATDP1L3MBTL1ALDH1A1LMNA | |
| SCHEMBL5954273 | 0.85 | TLR4 (0.39) | TLR4ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL27693071 | 0.84 | TLR4 (0.50) | TLR4GAATDP1L3MBTL1ALDH1A1 | |
| SCHEMBL31612271 | 0.81 | ALDH1A1 (0.44) | TLR4TDP1ALDH1A1LMNAMAPT | |
| SCHEMBL31612273 | 0.81 | ALDH1A1 (0.44) | TLR4TDP1ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1107971-A1 | PORPHYRIN DERIVATIVES, THEIR USE IN PHOTODYNAMIC THERAPY AND MEDICAL DEVICES CONTAINING THEM | Destiny Pharma Limited (GB) | 2001-06-20 | — | — | EP | disclosed |
| WO-2000012512-A1 | PORPHYRIN DERIVATIVES, THEIR USE IN PHOTODYNAMIC THERAPY AND MEDICAL DEVICES CONTAINING THEM | DESTINY PHARMA LIMITED (GB) | 2000-03-09 | — | — | WO | disclosed |