Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7868898 | 1.00 | TLR4 (0.47) | TLR4GAATDP1L3MBTL1ALDH1A1 | |
| SCHEMBL19710403 | 0.93 | GAA (0.48) | TLR4GAATDP1L3MBTL1ALDH1A1 | |
| SCHEMBL5954267 | 0.89 | TLR4 (0.45) | TLR4ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL1242931 | 0.86 | NPC1 (0.52) | GAATDP1L3MBTL1ALDH1A1LMNA | |
| SCHEMBL11439257 | 0.86 | NPC1 (0.52) | GAATDP1L3MBTL1ALDH1A1LMNA | |
| SCHEMBL28004812 | 0.86 | NPC1 (0.52) | GAATDP1L3MBTL1ALDH1A1LMNA | |
| SCHEMBL5954273 | 0.85 | TLR4 (0.39) | TLR4ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL27693071 | 0.84 | TLR4 (0.50) | TLR4GAATDP1L3MBTL1ALDH1A1 | |
| SCHEMBL31612271 | 0.81 | ALDH1A1 (0.44) | TLR4TDP1ALDH1A1LMNAMAPT | |
| SCHEMBL31612273 | 0.81 | ALDH1A1 (0.44) | TLR4TDP1ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10056554-B2 | Functional interlayers of fullerene derivatives and applications in organic solar cells | UNIVERSITY OF MASSACHUSETTS (US) | 2018-08-21 | — | — | US | disclosed |
| US-20170047520-A1 | FUNCTIONAL INTERLAYERS OF FULLERENE DERIVATIVES AND APPLICATIONS IN ORGANIC SOLAR CELLS | UNIVERSITY OF MASSACHUSETTS (US) | 2017-02-16 | — | — | US | disclosed |
| US-20170047520-A1 | FUNCTIONAL INTERLAYERS OF FULLERENE DERIVATIVES AND APPLICATIONS IN ORGANIC SOLAR CELLS | UNIVERSITY OF MASSACHUSETTS (US) | 2017-02-16 | — | — | US | disclosed |
| US-20170047520-A1 | FUNCTIONAL INTERLAYERS OF FULLERENE DERIVATIVES AND APPLICATIONS IN ORGANIC SOLAR CELLS | UNIVERSITY OF MASSACHUSETTS (US) | 2017-02-16 | — | — | US | disclosed |
| WO-2015171689-A1 | FUNCTIONAL INTERLAYERS OF FULLERENE DERIVATIVES AND APPLICATIONS IN ORGANIC SOLAR CELLS | UNIVERSITY OF MASSACHUSETTS (US) | 2015-11-12 | — | — | WO | disclosed |
| WO-2015171689-A1 | FUNCTIONAL INTERLAYERS OF FULLERENE DERIVATIVES AND APPLICATIONS IN ORGANIC SOLAR CELLS | UNIVERSITY OF MASSACHUSETTS (US) | 2015-11-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170047520-A1 | FUNCTIONAL INTERLAYERS OF FULLERENE DERIVATIVES AND APPLICATIONS IN ORGANIC SOLAR CELLS | PPOX, OCIAD2, PIN4 | TLR4 3258/4885GAA 4771/4885TDP1 3600/4885 |
| US-10056554-B2 | Functional interlayers of fullerene derivatives and applications in organic solar cells | PPOX, OCIAD2, PIN4 | TLR4 3258/4885GAA 4771/4885TDP1 3600/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.