SCHEMBL7869032

SCHEMBL7869032

CC(=O)Nc1cc(Cl)ccc1CCOC(C)=O

nearest known ligand 0.48

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.48
HPGD P15428 2/20 0.48
USP2 O75604 1/20 0.48
KDM4E B2RXH2 1/20 0.47
HSD17B10 Q99714 1/20 0.47
LMNA P02545 2/20 0.44
KMT2A Q03164 5/20 0.42
CCR1 P32246 1/20 0.42
GAA P10253 1/20 0.42
MEN1 O00255 4/20 0.42
ALDH1A1 P00352 3/20 0.42
EPHX1 P07099 1/20 0.40
POLB P06746 1/20 0.40
CYP1A2 P05177 1/20 0.39
CYP2C19 P33261 1/20 0.39
SIRT2 Q8IXJ6 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5101521 0.89 USP2 (0.51) SMN1; SMN2HPGDUSP2KDM4EHSD17B10
SCHEMBL7872576 0.82 KDM4E (0.51) SMN1; SMN2KDM4EHSD17B10LMNAKMT2A
SCHEMBL27949329 0.80 HPGD (0.50) HPGDUSP2LMNAGAAALDH1A1
SCHEMBL23524965 0.80 KDM4E (0.56) SMN1; SMN2HPGDKDM4EHSD17B10LMNA
SCHEMBL29085138 0.80 CYP2C19 (0.55) HPGDUSP2KDM4EHSD17B10KMT2A
SCHEMBL8616388 0.79 ALDH1A1 (0.49) SMN1; SMN2HPGDKDM4EHSD17B10LMNA
SCHEMBL9523590 0.79 SMN1; SMN2 (0.57) SMN1; SMN2HPGDLMNAKMT2AMEN1
SCHEMBL9373094 0.79 KDM4E (0.54) SMN1; SMN2KDM4EHSD17B10LMNAKMT2A
SCHEMBL9373680 0.79 KDM4E (0.54) SMN1; SMN2KDM4EHSD17B10LMNAKMT2A
SCHEMBL5213501 0.77 KDM4E (0.49) SMN1; SMN2HPGDKDM4EHSD17B10LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6306179-B1 FOR DYEING HAIR L'OREAL S.A. (FR) 2001-10-23 US disclosed