Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | CCR1 | P32246 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9373094 | 0.87 | KDM4E (0.54) | KDM4EHSD17B10LMNAEPHX1KMT2A | |
| SCHEMBL23524965 | 0.85 | KDM4E (0.56) | KDM4EHSD17B10LMNAEPHX1KMT2A | |
| SCHEMBL9373680 | 0.83 | KDM4E (0.54) | KDM4EHSD17B10CCR1LMNAEPHX1 | |
| SCHEMBL7869032 | 0.82 | SMN1; SMN2 (0.48) | KDM4EHSD17B10CCR1LMNAEPHX1 | |
| SCHEMBL12393157 | 0.80 | ALDH1A1 (0.42) | KDM4ELMNAKMT2AMEN1POLB | |
| SCHEMBL30105032 | 0.79 | MEN1 (0.50) | LMNAKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL23831629 | 0.79 | MEN1 (0.50) | LMNAKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL5213501 | 0.78 | KDM4E (0.49) | KDM4EHSD17B10LMNAEPHX1KMT2A | |
| SCHEMBL3782005 | 0.77 | KDM4E (0.68) | KDM4EHSD17B10EPHX1KMT2AMEN1 | |
| SCHEMBL23831843 | 0.77 | MEN1 (0.62) | KDM4EHSD17B10LMNAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6306179-B1 | FOR DYEING HAIR | L'OREAL S.A. (FR) | 2001-10-23 | — | — | US | disclosed |
| EP-0911317-B1 | Process for the preparation of 2-hydroyalkyl paraphenylenediamines, novel 2-hydroxyalkyl paraphenylenediamines, their use for oxydative dyeing, dye compositions and dyeing processes | OREAL (FR) | 2000-09-13 | — | — | EP | disclosed |
| EP-0911317-A1 | Process for the preparation of 2-hydroyalkyl paraphenylenediamines, novel 2-hydroxyalkyl paraphenylenediamines, their use for oxydative dyeing, dye compositions and dyeing processes | L'OREAL (FR) | 1999-04-28 | — | — | EP | disclosed |