Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 1/20 | 0.51 |
| ▸ | CD274 | Q9NZQ7 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8494593 | 0.86 | HPGDS (0.48) | HPGDSCD274SMN1; SMN2HPGD | |
| SCHEMBL7869778 | 0.86 | HPGDS (0.48) | HPGDSCD274SMN1; SMN2HPGD | |
| SCHEMBL7869009 | 0.86 | PRKAA2 (0.44) | SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7868143 | 0.86 | HPGDS (0.47) | HPGDSCD274SMN1; SMN2HPGD | |
| SCHEMBL8494682 | 0.82 | SMN1; SMN2 (0.55) | CD274SMN1; SMN2HPGDALDH1A1HTR1A | |
| SCHEMBL8491403 | 0.82 | KMT2A (0.43) | SMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7869101 | 0.81 | SMN1; SMN2 (0.54) | HPGDSCD274SMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL7873110 | 0.81 | PRMT5 (0.46) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL8495364 | 0.80 | ALOX15 (0.47) | HPGDALDH1A1 | |
| Hydrochloric Acid SCHEMBL7866438 | 0.79 | ALOX15 (0.46) | HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6306860-B1 | ANTIVIRAL ACTIVITIES AGAINST HEPATATIS B AS WELL AS HUMAN IMMUNODEFICIENCY VIRUS | DONG WHA PHARM. INC. CO., LTD. (KR) | 2001-10-23 | — | — | US | disclosed |