SCHEMBL7869288

SCHEMBL7869288

N#Cc1c(F)c(F)c(Oc2c(F)c(F)cc(F)c2F)c(F)c1C#N

nearest known ligand 0.38

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TRPV4 Q9HBA0 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3619566 0.87 TRPV4 (0.31) TRPV4
SCHEMBL13439997 0.85 TRPV4 (0.30) TRPV4
SCHEMBL9140608 0.82 TRPV4 (0.33) TRPV4
SCHEMBL9618395 0.81
SCHEMBL13407366 0.78 KDM4E (0.30)
SCHEMBL4594176 0.78
SCHEMBL4594106 0.78 MEN1 (0.36)
SCHEMBL29464019 0.78 CA1 (0.36)
SCHEMBL4594009 0.76 ALDH1A1 (0.34)
SCHEMBL4593960 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0882768-B1 Method for producing of phthalocyanine compound NIPPON CATALYTIC CHEM IND (JP) 2001-12-19 EP disclosed
US-6034236-A REACTING A PHTHALONITRILE WITH A METAL OXIDE IN PRESENCE OF A SULFONIC ACID CATALYST NIPPON SHOKUBAI CO., LTD. (JP) 2000-03-07 US disclosed
EP-0882768-A2 Method for producing of phthalocyanine compound NIPPON SHOKUBAI CO., LTD. (JP) 1998-12-09 EP disclosed