Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.44 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7871575 | 0.93 | KMT2A (0.56) | KMT2AMEN1P4HTMLMNAALDH1A1 | |
| SCHEMBL7874499 | 0.93 | P4HTM (0.58) | KMT2AMEN1P4HTMALDH1A1MAPT | |
| SCHEMBL7870457 | 0.91 | SMN1; SMN2 (0.53) | KMT2AMEN1P4HTMLMNAALDH1A1 | |
| SCHEMBL9574879 | 0.91 | NPC1 (0.52) | KMT2AMEN1ALDH1A1MAPTRAB9A | |
| SCHEMBL7867790 | 0.90 | MEN1 (0.48) | KMT2AMEN1P4HTMLMNAMAPT | |
| SCHEMBL7869444 | 0.90 | KMT2A (0.53) | KMT2AMEN1P4HTMLMNAALDH1A1 | |
| SCHEMBL7871641 | 0.90 | CA1 (0.56) | KMT2AMEN1LMNAALDH1A1MAPT | |
| SCHEMBL7867837 | 0.89 | NLRP3 (0.51) | KMT2AMEN1P4HTMLMNAALDH1A1 | |
| SCHEMBL7869433 | 0.89 | MAPT (0.50) | KMT2AMEN1LMNAMAPTRAB9A | |
| SCHEMBL7874505 | 0.89 | EGFR (0.53) | KMT2AMEN1MAPTRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0562512-B1 | Sulfonamidocarbonylpyridine-2-carboxamides and their use as medicines | HOECHST AG (DE) | 2001-02-21 | — | — | EP | disclosed |
| EP-0562512-A1 | Sulfonamido- and sulfonamidocarbonyl-pyridine-2-carboxamides and their pyridine-N-oxides, process for their preparation and their use as medicines | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-09-29 | — | — | EP | disclosed |