Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | EGFR | P00533 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7869464 | 0.93 | KMT2A (0.56) | P4HTMMEN1KMT2ACA1CA2 | |
| SCHEMBL9574906 | 0.90 | P4HTM (0.56) | P4HTMMEN1KMT2AEGFRHSD17B10 | |
| SCHEMBL9574699 | 0.90 | P4HTM (0.60) | P4HTMMEN1KMT2AEGFRHSD17B10 | |
| SCHEMBL7871651 | 0.89 | BCL2L1 (0.46) | P4HTMMEN1KMT2AEGFRHDAC3 | |
| SCHEMBL7871681 | 0.88 | EGFR (0.46) | P4HTMEGFRCA1CA2FLT1 | |
| SCHEMBL7869455 | 0.87 | P4HTM (0.57) | P4HTMEGFRRAB9ASMN1; SMN2 | |
| SCHEMBL7874560 | 0.87 | SCN3A (0.44) | P4HTMEGFRHDAC3HDAC4HDAC1 | |
| SCHEMBL7869468 | 0.86 | EPHX2 (0.44) | P4HTMMEN1KMT2AEGFRRAB9A | |
| SCHEMBL7874570 | 0.86 | EGFR (0.44) | P4HTMMEN1KMT2AEGFRHSD17B10 | |
| SCHEMBL7867837 | 0.86 | NLRP3 (0.51) | P4HTMMEN1KMT2AALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0562512-B1 | Sulfonamidocarbonylpyridine-2-carboxamides and their use as medicines | HOECHST AG (DE) | 2001-02-21 | — | — | EP | disclosed |
| EP-0562512-A1 | Sulfonamido- and sulfonamidocarbonyl-pyridine-2-carboxamides and their pyridine-N-oxides, process for their preparation and their use as medicines | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-09-29 | — | — | EP | disclosed |