SCHEMBL786957

SCHEMBL786957

CC(CCC[Si](C)(C)O[Si](O[Si](C)(C)CCCCCC(=O)O)(O[Si](C)(C)CCCC(C)C(=O)O)c1ccccc1)C(=O)O

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MME P08473 2/20 0.37
ACE P12821 2/20 0.37
CYP1A2 P05177 1/20 0.36
LTB4R Q15722 8/20 0.36
TBXAS1 P24557 1/20 0.36
HDAC3 O15379 2/20 0.35
HDAC4 P56524 2/20 0.35
HDAC1 Q13547 2/20 0.35
HDAC2 Q92769 2/20 0.35
HDAC10 Q969S8 2/20 0.35
HDAC11 Q96DB2 2/20 0.35
HDAC8 Q9BY41 2/20 0.35
HDAC6 Q9UBN7 2/20 0.35
HDAC5 Q9UQL6 2/20 0.35
MAPT P10636 1/20 0.35
RXFP1 Q9HBX9 1/20 0.35
HDAC7 Q8WUI4 1/20 0.35
HDAC9 Q9UKV0 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
LTA4H P09960 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL786863 0.85 MME (0.34) MMEACECYP1A2LTB4RTBXAS1
SCHEMBL13042907 0.78 CPA1 (0.41) LTA4H
SCHEMBL786837 0.75 CYP1A2 (0.37) CYP1A2LTA4H
SCHEMBL18227249 0.72 HDAC3 (0.41) HDAC3HDAC4HDAC1HDAC2HDAC10
SCHEMBL786853 0.72 FFAR4 (0.50) CYP1A2HDAC11MAPTNPSR1
SCHEMBL15761478 0.71 FFAR1 (0.38)
SCHEMBL1054764 0.71 TSHR (0.52) HDAC11
SCHEMBL23908692 0.69 LMNA (0.50) HDAC11
SCHEMBL2835395 0.69 CYP1A2 (0.67) CYP1A2HDAC11LTA4H
Pimelic Acid SCHEMBL8471838 0.69 CYP1A2 (0.67) CYP1A2HDAC11LTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150166342-A1 Functionalized Matrices for Dispersion of Nanostructures NANOSYS, INC. (US) 2015-06-18 US disclosed
US-8916064-B2 Functionalized matrices for dispersion of nanostructures NANOSYS, INC. (US) 2014-12-23 US disclosed
US-20140151600-A1 Functionalized Matrices for Dispersion of Nanostructures NANOSYS, INC. (US) 2014-06-05 US disclosed
US-20130043433-A1 Functionalized Matrixes for Dispersion of Nanostructures NANOSYS, INC. (US) 2013-02-21 US disclosed
US-20120068118-A1 NANOCRYSTAL DOPED MATRIXES SAMSUNG ELECTRONICS CO., LTD. (KR) 2012-03-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120068118-A1 NANOCRYSTAL DOPED MATRIXES STRA6, EPHA6, PIR MME 129/4885ACE 587/4885CYP1A2 4339/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.