Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 9/20 | 0.80 |
| ▸ | GRIN2B | Q13224 | 9/20 | 0.80 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.80 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.71 |
| ▸ | TP53 | P04637 | 1/20 | 0.71 |
| ▸ | MAPT | P10636 | 1/20 | 0.71 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.68 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.68 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.68 |
| ▸ | GPBAR1 | Q8TDU6 | 4/20 | 0.65 |
| ▸ | LMNA | P02545 | 3/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.65 |
| ▸ | SHBG | P04278 | 2/20 | 0.65 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.65 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.65 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.65 |
| ▸ | G6PD | P11413 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17006954 | 1.00 | GRIN1 (0.80) | GRIN1GRIN2BMAPK1ALDH1A1TP53 | |
| SCHEMBL30421845 | 1.00 | GRIN1 (0.80) | GRIN1GRIN2BMAPK1ALDH1A1TP53 | |
| SCHEMBL235684 | 1.00 | GRIN1 (0.80) | GRIN1GRIN2BMAPK1ALDH1A1TP53 | |
| SCHEMBL235685 | 1.00 | GRIN1 (0.80) | GRIN1GRIN2BMAPK1ALDH1A1TP53 | |
| SCHEMBL17006955 | 1.00 | GRIN1 (0.80) | GRIN1GRIN2BMAPK1ALDH1A1TP53 | |
| SCHEMBL8581388 | 1.00 | GRIN1 (0.80) | GRIN1GRIN2BMAPK1ALDH1A1TP53 | |
| SCHEMBL332917 | 1.00 | GRIN1 (0.80) | GRIN1GRIN2BMAPK1ALDH1A1TP53 | |
| SCHEMBL2079281 | 1.00 | GRIN1 (0.80) | GRIN1GRIN2BMAPK1ALDH1A1TP53 | |
| SCHEMBL136323 | 1.00 | GRIN1 (0.80) | GRIN1GRIN2BMAPK1ALDH1A1TP53 | |
| SCHEMBL136324 | 1.00 | GRIN1 (0.80) | GRIN1GRIN2BMAPK1ALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6326209-B1 | STEROIDS USED FOR AGE DETERMINATION | UNIVERA PHARMACEUTICALS, INC. | 2001-12-04 | — | — | US | disclosed |