Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 9/20 | 0.80 |
| ▸ | GRIN2B | Q13224 | 9/20 | 0.80 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.80 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.71 |
| ▸ | TP53 | P04637 | 1/20 | 0.71 |
| ▸ | MAPT | P10636 | 1/20 | 0.71 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.68 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.68 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.68 |
| ▸ | GPBAR1 | Q8TDU6 | 4/20 | 0.65 |
| ▸ | LMNA | P02545 | 3/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.65 |
| ▸ | SHBG | P04278 | 2/20 | 0.65 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.65 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.65 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.65 |
| ▸ | G6PD | P11413 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17006954 | 1.00 | GRIN1 (0.80) | GRIN1GRIN2BMAPK1ALDH1A1TP53 | |
| SCHEMBL30421845 | 1.00 | GRIN1 (0.80) | GRIN1GRIN2BMAPK1ALDH1A1TP53 | |
| SCHEMBL235684 | 1.00 | GRIN1 (0.80) | GRIN1GRIN2BMAPK1ALDH1A1TP53 | |
| SCHEMBL235685 | 1.00 | GRIN1 (0.80) | GRIN1GRIN2BMAPK1ALDH1A1TP53 | |
| SCHEMBL7869703 | 1.00 | GRIN1 (0.80) | GRIN1GRIN2BMAPK1ALDH1A1TP53 | |
| SCHEMBL17006955 | 1.00 | GRIN1 (0.80) | GRIN1GRIN2BMAPK1ALDH1A1TP53 | |
| SCHEMBL8581388 | 1.00 | GRIN1 (0.80) | GRIN1GRIN2BMAPK1ALDH1A1TP53 | |
| SCHEMBL332917 | 1.00 | GRIN1 (0.80) | GRIN1GRIN2BMAPK1ALDH1A1TP53 | |
| SCHEMBL136323 | 1.00 | GRIN1 (0.80) | GRIN1GRIN2BMAPK1ALDH1A1TP53 | |
| SCHEMBL136324 | 1.00 | GRIN1 (0.80) | GRIN1GRIN2BMAPK1ALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023083020-A1 | USE OF SERUM METABOLIC MARKER FOR DETECTING EGFR MUTATION AND DETECTION SYSTEM | 中山大学肿瘤防治中心（中山大学附属肿瘤医院、中山大学肿瘤研究所） | 2023-05-19 | — | — | WO | claimed |
| EP-3502703-A1 | METHOD FOR THE ASSESSMENT OF NAFLD | Metanomics Health GmbH (DE) | 2019-06-26 | — | — | EP | claimed |
| EP-4608876-A2 | ENDOCYTIC AGENTS | BioVentures, LLC (US) | 2025-09-03 | — | — | EP | disclosed |
| US-20250166821-A1 | METHODS FOR PREDICTION OF TREATMENT RESPONSE IN NON-ALCOHOLIC FATTY LIVER DISEASE | SAGIMET BIOSCIENCES INC. | 2025-05-22 | — | — | US | disclosed |
| US-12076377-B2 | Variant sulfatase enzymes with enhanced properties | INTEGRATED MICRO-CHROMATOGRAPHY SYSTEMS, INC. (US) | 2024-09-03 | — | — | US | disclosed |
| WO-2024092274-A2 | ENDOCYTIC AGENTS | BIOVENTURES, LLC (US) | 2024-05-02 | — | — | WO | disclosed |
| WO-2023083020-A1 | USE OF SERUM METABOLIC MARKER FOR DETECTING EGFR MUTATION AND DETECTION SYSTEM | 中山大学肿瘤防治中心（中山大学附属肿瘤医院、中山大学肿瘤研究所） | 2023-05-19 | — | — | WO | disclosed |
| US-20230149519-A1 | VARIANT SULFATASE ENZYMES WITH ENHANCED PROPERTIES | INTEGRATED MICRO-CHROMATOGRAPHY SYSTEMS, INC. | 2023-05-18 | — | — | US | disclosed |
| US-20230107049-A1 | ANALYSIS OF MICROBIOME FOR DIAGNOSIS AND TREATING OF URINARY STONE DISEASE | UNIVERSITY OF UTAH | 2023-04-06 | — | — | US | disclosed |
| EP-3502703-A1 | METHOD FOR THE ASSESSMENT OF NAFLD | Metanomics Health GmbH (DE) | 2019-06-26 | — | — | EP | disclosed |
| WO-2012049874-A1 | BIOMARKER FOR DIAGNOSIS OF FATTY LIVER DISEASES, METHOD FOR MEASURING SAME, COMPUTER PROGRAM AND STORAGE MEDIUM | ヒューマン・メタボローム・テクノロジーズ株式会社 (JP) | 2012-04-19 | — | — | WO | disclosed |
| US-20020064883-A1 | Measurement and quantification of 17 ketosteroid-sulfates as a biomarker of biological age | UNIGEN PHARMACEUTICALS, INC. | 2002-05-30 | — | — | US | disclosed |
| US-6326209-B1 | STEROIDS USED FOR AGE DETERMINATION | UNIVERA PHARMACEUTICALS, INC. | 2001-12-04 | — | — | US | disclosed |
| US-5811248-A | Atherosclerotic plaque specific antigens, antibodies thereto, and uses thereof | CHARTER VENTURES (US) | 1998-09-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250166821-A1 | METHODS FOR PREDICTION OF TREATMENT RESPONSE IN NON-ALCOHOLIC FATTY LIVER DISEASE | ACACB, ACACA, ACLY | GRIN1 3745/4885GRIN2B 4695/4885MAPK1 3525/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.