Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 15/20 | 0.76 |
| ▸ | PDE4D | Q08499 | 15/20 | 0.76 |
| ▸ | PDE4A | P27815 | 14/20 | 0.76 |
| ▸ | PDE4C | Q08493 | 14/20 | 0.76 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7416733 | 0.86 | PDE4B (1.00) | PDE4BPDE4DPDE4APDE4CLMNA | |
| SCHEMBL6322995 | 0.85 | PDE4B (0.74) | PDE4BPDE4DPDE4APDE4CLMNA | |
| SCHEMBL6322447 | 0.85 | PDE4B (0.74) | PDE4BPDE4DPDE4APDE4CLMNA | |
| SCHEMBL6323001 | 0.85 | PDE4B (0.74) | PDE4BPDE4DPDE4APDE4CLMNA | |
| SCHEMBL7858785 | 0.80 | PDE4B (0.73) | PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL7864287 | 0.80 | PDE4B (0.75) | PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL7420740 | 0.80 | PDE4A (0.66) | PDE4BPDE4DPDE4APDE4CLMNA | |
| SCHEMBL7858810 | 0.78 | PDE4B (0.73) | PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL7858781 | 0.78 | PDE4A (0.73) | PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL7869861 | 0.78 | PDE4B (0.73) | PDE4BPDE4DPDE4APDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0636025-B1 | COMPOUNDS USEFUL FOR TREATING ALLERGIC OR INFLAMMATORY DISEASES | SMITHKLINE BEECHAM CORP (US) | 2001-07-18 | — | — | EP | claimed |