Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 18/20 | 0.74 |
| ▸ | PDE4D | Q08499 | 18/20 | 0.74 |
| ▸ | PDE4A | P27815 | 17/20 | 0.74 |
| ▸ | PDE4C | Q08493 | 17/20 | 0.74 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6323001 | 1.00 | PDE4B (0.74) | PDE4BPDE4DPDE4APDE4CLMNA | |
| SCHEMBL6322447 | 1.00 | PDE4B (0.74) | PDE4BPDE4DPDE4APDE4CLMNA | |
| SCHEMBL8344453 | 0.87 | PDE4B (0.71) | PDE4BPDE4DPDE4APDE4CPOLB | |
| SCHEMBL14473185 | 0.86 | PDE4A (0.76) | PDE4BPDE4DPDE4APDE4CPOLB | |
| SCHEMBL13790344 | 0.86 | PDE4A (0.76) | PDE4BPDE4DPDE4APDE4CPOLB | |
| SCHEMBL7869812 | 0.85 | PDE4B (0.76) | PDE4BPDE4DPDE4APDE4CLMNA | |
| SCHEMBL7416733 | 0.85 | PDE4B (1.00) | PDE4BPDE4DPDE4APDE4CLMNA | |
| SCHEMBL7359174 | 0.83 | PDE4B (0.82) | PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL7363153 | 0.83 | PDE4B (0.82) | PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL7359794 | 0.83 | PDE4A (0.71) | PDE4BPDE4DPDE4APDE4CPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050137416-A1 | Process and intermediates for preparing a cyclohexylnitrile | SMITHKLINE BEECHAM CORPORATION | 2005-06-23 | — | — | US | disclosed |
| US-20030050497-A1 | Process and intermediates for preparing a cyclohexylnitrile | SMITHKLINE BEECHAM CORPORATION | 2003-03-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050137416-A1 | Process and intermediates for preparing a cyclohexylnitrile | HPD, PCCA, MCCC2 | PDE4B 2828/4885PDE4D 3281/4885PDE4A 2567/4885 |
| US-20030050497-A1 | Process and intermediates for preparing a cyclohexylnitrile | HPD, PCCA, MCCC2 | PDE4B 2785/4885PDE4D 3239/4885PDE4A 2549/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.