Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 5/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.30 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.30 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1344288 | 0.83 | PSEN1 (0.36) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7387551 | 0.70 | PDE4B (0.67) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL14482440 | 0.68 | PDE4A (0.36) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL28879187 | 0.65 | FFAR4 (0.33) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL27735651 | 0.65 | FFAR4 (0.32) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL5306792 | 0.65 | PDE4B (0.53) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL27600726 | 0.64 | SYK (0.43) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL28332625 | 0.63 | ADRA2A (0.35) | PDE4B | |
| SCHEMBL7963641 | 0.63 | PSEN1 (0.41) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL2290555 | 0.62 | PDE4B (0.63) | PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0636025-B1 | COMPOUNDS USEFUL FOR TREATING ALLERGIC OR INFLAMMATORY DISEASES | SMITHKLINE BEECHAM CORP (US) | 2001-07-18 | — | — | EP | claimed |