Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 1/20 | 0.36 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.36 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.36 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.36 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.36 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 3/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7869823 | 0.83 | PDE4A (0.39) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL4430870 | 0.79 | PSEN1 (0.44) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL7416606 | 0.76 | PDE4B (0.60) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8356325 | 0.75 | PSEN1 (0.46) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL17542850 | 0.73 | PSEN1 (0.52) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL29360419 | 0.72 | PDE4B (0.49) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL109922 | 0.72 | PDE4B (0.49) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL1558214 | 0.69 | RORC (0.45) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL11096494 | 0.69 | PSEN1 (0.47) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL6617848 | 0.69 | PDE4A (0.39) | PSEN1PSEN2APH1BNCSTNAPH1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8061350-B2 | Process and device for dosing pharmaceutical agents | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2011-11-22 | — | — | US | disclosed |
| US-20070282276-A1 | PROCESS AND DEVICE FOR DOSING PHARMACEUTICAL AGENTS | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2007-12-06 | — | — | US | disclosed |