Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7873976 | 0.82 | MAPT (0.59) | MAPTKMT2ACYP1A2CYP2C19NPC1 | |
| SCHEMBL7862107 | 0.81 | MAPT (0.58) | MAPTKMT2ACYP1A2CYP2C19NPC1 | |
| SCHEMBL7869922 | 0.80 | MAPT (0.56) | MAPTKMT2ACYP1A2CYP2C19NPC1 | |
| SCHEMBL7866981 | 0.79 | SMN1; SMN2 (0.65) | MAPTNPC1RAB9AALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7868840 | 0.79 | MAPT (0.55) | MAPTKMT2ACYP1A2CYP2C19NPC1 | |
| SCHEMBL7873626 | 0.78 | NPSR1 (0.57) | KMT2ANPC1RAB9AMEN1ALDH1A1 | |
| SCHEMBL7868846 | 0.77 | ALDH1A1 (0.63) | MAPTKMT2ACYP1A2CYP2C19NPC1 | |
| SCHEMBL5155315 | 0.76 | MAPT (0.66) | MAPTKMT2ACYP1A2CYP2C19RAB9A | |
| SCHEMBL2466960 | 0.75 | KDM4E (0.87) | MAPTCYP1A2CYP2C19ALDH1A1CYP2D6 | |
| SCHEMBL7868780 | 0.74 | SMN1; SMN2 (0.61) | MAPTKMT2ACYP1A2CYP2C19MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6300368-B1 | FOR THERAPY OF ATRIAL ARRHYTHMIA | MITSUI CHEMICALS, INC. (JP) | 2001-10-09 | — | — | US | disclosed |
| EP-0968999-A1 | Anilide derivatives and antiarrhythmic agents containing the same | Mitsui Chemicals, Inc. (JP) | 2000-01-05 | — | — | EP | disclosed |