Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7868840 | 0.99 | MAPT (0.55) | MAPTNPC1RAB9AKMT2ACYP1A2 | |
| Hydrochloric Acid SCHEMBL7873976 | 0.84 | MAPT (0.59) | MAPTNPC1RAB9AKMT2ACYP1A2 | |
| SCHEMBL7866908 | 0.83 | MAPT (0.50) | MAPTNPC1RAB9AKMT2ACYP1A2 | |
| SCHEMBL7862107 | 0.83 | MAPT (0.58) | MAPTNPC1RAB9AKMT2ACYP1A2 | |
| SCHEMBL7873618 | 0.82 | MEN1 (0.64) | MAPTKMT2ACYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL8003660 | 0.82 | NPSR1 (0.50) | MAPTNPC1RAB9ACYP1A2CYP2C19 | |
| SCHEMBL7862182 | 0.82 | NPC1 (0.46) | MAPTNPC1RAB9AKMT2AMEN1 | |
| SCHEMBL7866950 | 0.82 | LMNA (0.48) | MAPTRAB9AKMT2ASMN1; SMN2MEN1 | |
| Hydrochloric Acid SCHEMBL7874134 | 0.81 | LMNA (0.47) | MAPTRAB9AKMT2ASMN1; SMN2MEN1 | |
| Hydrochloric Acid SCHEMBL7866916 | 0.81 | MEN1 (0.63) | MAPTKMT2ACYP1A2CYP2C19SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6300368-B1 | FOR THERAPY OF ATRIAL ARRHYTHMIA | MITSUI CHEMICALS, INC. (JP) | 2001-10-09 | — | — | US | disclosed |
| EP-0968999-A1 | Anilide derivatives and antiarrhythmic agents containing the same | Mitsui Chemicals, Inc. (JP) | 2000-01-05 | — | — | EP | disclosed |