⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23640408 | 0.92 | — | — | |
| SCHEMBL12603472 | 0.90 | HDAC3 (0.50) | — | |
| SCHEMBL1146799 | 0.83 | — | — | |
| SCHEMBL7753090 | 0.83 | LMNA (0.57) | — | |
| SCHEMBL5909180 | 0.83 | LMNA (0.57) | — | |
| SCHEMBL6159056 | 0.80 | HDAC3 (0.55) | — | |
| SCHEMBL29315161 | 0.80 | HDAC3 (0.55) | — | |
| SCHEMBL12333287 | 0.80 | HDAC3 (0.55) | — | |
| SCHEMBL5909431 | 0.80 | HDAC3 (0.55) | — | |
| SCHEMBL5909483 | 0.80 | HDAC3 (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4298686-A | HIGH SENSITIVITY, AUTOMATIC | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 1981-11-03 | — | — | US | claimed |
| CN-110382532-B | anti-G-CSF antibodies and uses thereof | ME医疗公司 | 2023-04-14 | — | — | CN | disclosed |
| US-20230115871-A1 | A CONJUGATE OF A CYTOTOXIC AGENT TO A CELL BINDING MOLECULE WITH BRANCHED LINKERS | HANGZHOU DAC BIOTECH CO., LTD (CN) | 2023-04-13 | — | — | US | disclosed |
| CN-115942978-A | Antibody-drug conjugates comprising anti-B7-H3 antibodies | 尹图赛利有限公司 | 2023-04-07 | — | — | CN | disclosed |
| EP-3210627-B1 | CONJUGATES OF CELL BINDING MOLECULES WITH CYTOTOXIC AGENTS | HANGZHOU DAC BIOTECH CO LTD (CN) | 2022-12-21 | — | — | EP | disclosed |
| CN-109689689-B | Glucocorticoid-induced tumor necrosis factor receptor (GITR) antibodies and methods of use thereof | 丹娜法伯癌症研究所公司 | 2022-12-06 | — | — | CN | disclosed |
| CN-114874331-A | Therapeutic antibodies and their use | 辉瑞公司 | 2022-08-09 | — | — | CN | disclosed |
| CN-114773476-A | Therapeutic antibodies and their use | 辉瑞公司 | 2022-07-22 | — | — | CN | disclosed |
| CN-108136002-B | Therapeutic antibodies and their use | 辉瑞公司 | 2022-05-31 | — | — | CN | disclosed |
| CN-113683695-A | anti-CXCR 4 antibodies and antibody-drug conjugates | 辉瑞公司 | 2021-11-23 | — | — | CN | disclosed |
| EP-3348280-A1 | CONJUGATES OF CELL BINDING MOLECULES WITH CYTOTOXIC AGENTS | Hangzhou Dac Biotech Co., Ltd (CN) | 2018-07-18 | — | — | EP | disclosed |
| WO-2018051109-A1 | NOVEL CYTOTOXIC AGENTS AND CONJUGATES THEREOF | POLYTHERICS LIMITED (GB) | 2018-03-22 | — | — | WO | disclosed |
| US-20170296663-A1 | Conjugates of Cell Binding Molecules with Cytotoxic Agents | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2017-10-19 | — | — | US | disclosed |
| EP-3210627-A1 | CONJUGATES OF CELL BINDING MOLECULES WITH CYTOTOXIC AGENTS | Hangzhou Dac Biotech Co., Ltd (CN) | 2017-08-30 | — | — | EP | disclosed |
| WO-2017100602-A1 | AMINIMIDE COMPOSITIONS | PPG INDUSTRIES OHIO, INC. (US) | 2017-06-15 | — | — | WO | disclosed |
| US-20170166686-A1 | METHOD FOR PRODUCING AN AMINIMIDE | PPG INDUSTRIES OHIO, INC. | 2017-06-15 | — | — | US | disclosed |
| US-20170166789-A1 | STRUCTURAL ADHESIVE COMPOSITIONS | PPG INDUSTRIES OHIO, INC. | 2017-06-15 | — | — | US | disclosed |
| US-20170157262-A1 | CONJUGATES OF CELL BINDING MOLECULES WITH CYTOTOXIC AGENTS | HANGZHOU DAC BIOTECH CO., LTD (CN) | 2017-06-08 | — | — | US | disclosed |
| EP-2074121-B1 | CHYMASE INHIBITORS | BOEHRINGER INGELHEIM INT (DE) | 2016-11-30 | — | — | EP | disclosed |
| US-6306977-B1 | SOLID PHASE SYNTHESIS | E. I. DU PONT DE NEMOURS AND COMPANY | 2001-10-23 | — | — | US | disclosed |