Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | THRA | P10827 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | BID | P55957 | 3/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.39 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.39 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.39 |
| ▸ | SAE1 | Q9UBE0 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | EP300 | Q09472 | 1/20 | 0.39 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.39 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.39 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.39 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | F7 | P08709 | 3/20 | 0.37 |
| ▸ | F3 | P13726 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29256323 | 0.89 | TDP1 (0.49) | ALDH1A1TDP1BIDMCL1BCL2L1 | |
| SCHEMBL1003516 | 0.89 | TDP1 (0.49) | ALDH1A1TDP1BIDMCL1BCL2L1 | |
| SCHEMBL9350609 | 0.89 | TDP1 (0.49) | ALDH1A1TDP1BIDMCL1BCL2L1 | |
| SCHEMBL413662 | 0.89 | TDP1 (0.49) | ALDH1A1TDP1BIDMCL1BCL2L1 | |
| SCHEMBL21552431 | 0.89 | TDP1 (0.49) | ALDH1A1TDP1BIDMCL1BCL2L1 | |
| SCHEMBL8750967 | 0.89 | TDP1 (0.49) | ALDH1A1TDP1BIDMCL1BCL2L1 | |
| Ethylene Glycol SCHEMBL11518185 | 0.86 | TDP1 (0.46) | ALDH1A1TDP1BIDMCL1BCL2L1 | |
| SCHEMBL28578567 | 0.85 | THRA (0.50) | TDP1THRATHRBBIDMCL1 | |
| SCHEMBL6398467 | 0.85 | THRA (0.50) | TDP1THRATHRBBIDMCL1 | |
| SCHEMBL2123587 | 0.84 | SMN1; SMN2 (0.46) | ALDH1A1TDP1BIDMCL1BCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6307069-B1 | EASILY CLEAVABLE UNDER ACIDIC CONDITIONS; CONTAINING A COPOLYMERIZABLE UNSATURATED GROUP | DAI-ICHI KOGYO SEIYAKU CO., LTD. (JP) | 2001-10-23 | — | — | US | disclosed |