Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | IDO1 | P14902 | 3/20 | 0.45 |
| ▸ | TDO2 | P48775 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7286111 | 0.79 | MEN1 (0.51) | LMNASMN1; SMN2MEN1KMT2ATSHR | |
| SCHEMBL4667552 | 0.76 | IDO1 (0.54) | LMNASMN1; SMN2IDO1TDO2POLB | |
| SCHEMBL7429799 | 0.72 | IDO1 (0.50) | LMNASMN1; SMN2IDO1TDO2POLB | |
| SCHEMBL5546047 | 0.72 | IDO1 (0.50) | LMNASMN1; SMN2IDO1TDO2TSHR | |
| Hydrochloric Acid SCHEMBL9714844 | 0.71 | IDO1 (0.54) | LMNASMN1; SMN2IDO1TDO2POLB | |
| SCHEMBL7583717 | 0.71 | LMNA (0.51) | LMNASMN1; SMN2IDO1TDO2POLB | |
| SCHEMBL7876579 | 0.71 | LMNA (0.47) | LMNASMN1; SMN2IDO1TDO2POLB | |
| SCHEMBL5190981 | 0.69 | CYP3A4 (0.64) | LMNASMN1; SMN2IDO1TDO2TSHR | |
| SCHEMBL4669314 | 0.69 | CYP3A4 (0.64) | LMNASMN1; SMN2IDO1TDO2TSHR | |
| SCHEMBL423397 | 0.69 | LMNA (0.54) | LMNASMN1; SMN2IDO1TDO2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6313094-B1 | COMPOSITION FOR INHIBITING HUMAN IMMUNODEFICIENCY VIRUS REPLICATION | JAPAN ENERGY CORPORATION (JP) | 2001-11-06 | — | — | US | disclosed |
| EP-0490667-B1 | HIV protease inhibitors | JAPAN ENERGY CORP (JP) | 1999-06-09 | — | — | EP | disclosed |
| EP-0490667-A2 | HIV protease inhibitors | JAPAN ENERGY CORPORATION (JP) | 1992-06-17 | — | — | EP | disclosed |