Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | GABBR2 | O75899 | 3/20 | 0.47 |
| ▸ | GABBR1 | Q9UBS5 | 3/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.47 |
| ▸ | DRD3 | P35462 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.45 |
| ▸ | HRH1 | P35367 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9291592 | 0.95 | IDO1 (0.53) | LMNASMN1; SMN2GABBR2GABBR1CYP2C9 | |
| SCHEMBL11435521 | 0.83 | IDO1 (0.47) | LMNASMN1; SMN2GABBR2GABBR1CYP2C9 | |
| SCHEMBL167430 | 0.82 | ALOX15 (0.48) | LMNASMN1; SMN2GABBR2GABBR1CYP2D6 | |
| SCHEMBL10334662 | 0.81 | IDO1 (0.54) | SMN1; SMN2DRD3MEN1KMT2AHRH1 | |
| SCHEMBL9292752 | 0.81 | IDO1 (0.54) | SMN1; SMN2CYP2D6CYP2C19DRD3CYP3A4 | |
| SCHEMBL10334895 | 0.81 | IDO1 (0.50) | LMNASMN1; SMN2CYP2D6CYP2C19DRD3 | |
| SCHEMBL9292448 | 0.81 | MEN1 (0.48) | MEN1KMT2ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL11439746 | 0.81 | CHRM2 (0.46) | LMNADRD3CYP1A2TSHRSLC6A2 | |
| SCHEMBL9293047 | 0.80 | PTGS2 (0.49) | LMNASMN1; SMN2MEN1KMT2ASLC6A4 | |
| Hydrochloric Acid SCHEMBL8044031 | 0.80 | LMNA (0.47) | LMNASMN1; SMN2CYP2D6DRD3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329502-B1 | VIRICIDES AGAINST HUMAN IMMUNODEFICIENCY VIRUS; TREATMENT OF AIDS (ACQUIRED IMMUNE DEFICIENCY SYNDROME) | JAPAN ENERGY CORPORATION (JP) | 2001-12-11 | — | — | US | disclosed |
| US-6313094-B1 | COMPOSITION FOR INHIBITING HUMAN IMMUNODEFICIENCY VIRUS REPLICATION | JAPAN ENERGY CORPORATION (JP) | 2001-11-06 | — | — | US | disclosed |
| EP-0490667-B1 | HIV protease inhibitors | JAPAN ENERGY CORP (JP) | 1999-06-09 | — | — | EP | disclosed |
| EP-0490667-A2 | HIV protease inhibitors | JAPAN ENERGY CORPORATION (JP) | 1992-06-17 | — | — | EP | disclosed |
| US-4205087-A | ANTIARTHRITIC AGENTS | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1980-05-27 | — | — | US | disclosed |
| US-4205087-A | ANTIARTHRITIC AGENTS | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1980-05-27 | — | — | US | disclosed |