Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 6/20 | 0.41 |
| ▸ | RARG | P13631 | 6/20 | 0.41 |
| ▸ | RARA | P10276 | 5/20 | 0.41 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.38 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 5/20 | 0.36 |
| ▸ | SSTR5 | P35346 | 2/20 | 0.34 |
| ▸ | HNF4A | P41235 | 1/20 | 0.34 |
| ▸ | MAP3K14 | Q99558 | 2/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7571998 | 0.85 | — | — | |
| SCHEMBL7567313 | 0.82 | RXRA (0.50) | RARBRARGRARACYP26A1CYP26B1 | |
| SCHEMBL7503006 | 0.79 | RXRA (0.47) | RARBRARGRARACYP26A1CYP26B1 | |
| SCHEMBL7571992 | 0.76 | RARB (0.41) | RARBRARGRARACYP26A1RXRA | |
| SCHEMBL7573343 | 0.76 | RARB (0.40) | RARBRARGRARARXRAHDAC8 | |
| SCHEMBL6157408 | 0.73 | PTGS1 (0.43) | RARBRARGRARARXRAPTGS1 | |
| SCHEMBL6156126 | 0.73 | PTGS1 (0.43) | RARBRARGRARARXRAPTGS1 | |
| SCHEMBL8332049 | 0.72 | RARA (0.41) | RARBRARGRARACYP26A1CYP26B1 | |
| SCHEMBL8333554 | 0.72 | RARA (0.41) | RARBRARGRARACYP26A1CYP26B1 | |
| SCHEMBL9054043 | 0.71 | RARA (0.44) | RARBRARGRARACYP26A1CYP26B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6313163-B1 | ADMINISTERING 2,4-PENTADIENOIC ACID DERIVATIVE FOR THERAPY OF DISEASE OR CONDITION RESPONSIVE TO THERAPY BY RETINOIDS | ALLERGEN SALES, INC. | 2001-11-06 | — | — | US | disclosed |