Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.34 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.33 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.33 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 2/20 | 0.33 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | CTRC | Q99895 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21048984 | 0.84 | TSHR (0.44) | TSHRCYP2A6BACE1ALOX5KIF11 | |
| SCHEMBL11108795 | 0.76 | CYP2A6 (0.54) | TSHRCYP2A6BACE1ALOX5SMARCA2 | |
| SCHEMBL4860546 | 0.73 | BCAT2 (0.41) | TSHRBACE1ALOX5CYP2C9ALDH1A1 | |
| Hydrochloric Acid SCHEMBL4860555 | 0.73 | FOLH1 (0.51) | ALDH1A1HSD17B10 | |
| SCHEMBL4781603 | 0.72 | KIF11 (0.54) | TSHRBACE1KIF11CYP2C9ALDH1A1 | |
| SCHEMBL10661427 | 0.71 | TSHR (0.68) | TSHRCYP2A6KIF11CYP2C9ESR2 | |
| SCHEMBL30524348 | 0.69 | NPC1 (0.46) | TSHRKIF11CYP2C9CNR1CNR2 | |
| SCHEMBL7067289 | 0.69 | NPC1 (0.46) | TSHRKIF11CYP2C9CNR1CNR2 | |
| SCHEMBL28222653 | 0.69 | KIF11 (0.61) | TSHRBACE1KIF11CYP2C9ALDH1A1 | |
| Hydrogen Sulfide SCHEMBL27896845 | 0.68 | TSHR (0.56) | TSHRKIF11ESR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6303267-B1 | FOR OFFSET PRINTING PLATES OR COLOR PROOFS CAN BE PRODUCED FROM THE RECORDING MATERIAL | AGFA-GEVAERT (BE) | 2001-10-16 | — | — | US | disclosed |