Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNRHR | P30968 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8162514 | 1.00 | GNRHR (1.00) | GNRHR | |
| SCHEMBL7905285 | 0.86 | GNRHR (1.00) | GNRHR | |
| SCHEMBL7544172 | 0.84 | GNRHR (0.78) | GNRHR | |
| SCHEMBL7544164 | 0.84 | GNRHR (0.78) | GNRHR | |
| SCHEMBL7977280 | 0.80 | GNRHR (0.81) | GNRHR | |
| SCHEMBL7977286 | 0.80 | GNRHR (0.81) | GNRHR | |
| SCHEMBL8351223 | 0.79 | GNRHR (0.81) | GNRHR | |
| SCHEMBL8351221 | 0.79 | GNRHR (0.81) | GNRHR | |
| SCHEMBL8175980 | 0.78 | GNRHR (0.74) | GNRHR | |
| SCHEMBL8175977 | 0.78 | GNRHR (0.74) | GNRHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1068195-A1 | ANTAGONISTS OF GONADOTROPIN RELEASING HORMONE | Merck & Co., Inc. (US) | 2001-01-17 | — | — | EP | disclosed |
| US-6159975-A | Antagonists of gonadotropin releasing hormone | MERCK & CO., INC. (US) | 2000-12-12 | — | — | US | disclosed |
| WO-1999041251-A1 | ANTAGONISTS OF GONADOTROPIN RELEASING HORMONE | MERCK & CO., INC. (US) | 1999-08-19 | — | — | WO | disclosed |