Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 7/20 | 0.40 |
| ▸ | CA1 | P00915 | 4/20 | 0.40 |
| ▸ | CA9 | Q16790 | 4/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | CDK1 | P06493 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | YAP1 | P46937 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7871331 | 0.84 | CA2 (0.40) | CA2CA1CA9CA5ASMN1; SMN2 | |
| SCHEMBL8536174 | 0.80 | CA2 (0.51) | CA2CA1CA9CA5ASMN1; SMN2 | |
| SCHEMBL8536178 | 0.80 | CA2 (0.51) | CA2CA1CA9CA5ASMN1; SMN2 | |
| SCHEMBL7877620 | 0.80 | CDK1 (0.53) | GAAKMT2ACDK1KDM4EMEN1 | |
| SCHEMBL9196481 | 0.74 | CA2 (0.47) | CA2CA1CA9CA5ASMN1; SMN2 | |
| SCHEMBL9196479 | 0.74 | CA2 (0.47) | CA2CA1CA9CA5ASMN1; SMN2 | |
| SCHEMBL7871328 | 0.73 | HPGD (0.53) | CA2CA1CA9CA5ASMN1; SMN2 | |
| SCHEMBL7871329 | 0.73 | HPGD (0.53) | CA2CA1CA9CA5ASMN1; SMN2 | |
| SCHEMBL8539913 | 0.72 | CA2 (0.55) | CA2CA1CA9CA5ASMN1; SMN2 | |
| SCHEMBL7711055 | 0.70 | CA2 (0.56) | CA2CA1CA9CA5AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6331506-B1 | Disubstituted methylidene hydrazinophenyl sulfonylureas, process for their production and their use as herbicides and plant growth regulators | HOECHST SCHERING AGREVO GMBH (DE) | 2001-12-18 | — | — | US | disclosed |