SCHEMBL7871407

SCHEMBL7871407

Nc1ccc(Oc2ccc(C(c3ccc(Oc4ccc(N)cc4)cc3)(C(Cl)(Cl)Cl)C(Cl)(Cl)Cl)cc2)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.59
MAPT P10636 5/20 0.59
RAB9A P51151 4/20 0.59
NPC1 O15118 3/20 0.59
MAPK1 P28482 3/20 0.59
HPGD P15428 1/20 0.59
TDP1 Q9NUW8 3/20 0.58
CYP3A4 P08684 1/20 0.58
TSHR P16473 1/20 0.58
MAOA P21397 2/20 0.54
MAOB P27338 2/20 0.54
TEAD4 Q15561 1/20 0.48
SMN1; SMN2 Q16637 3/20 0.47
MEN1 O00255 3/20 0.47
KMT2A Q03164 3/20 0.47
POLB P06746 2/20 0.47
MITF O75030 1/20 0.47
GAA P10253 1/20 0.47
GFER P55789 1/20 0.47
NLRP1 Q9C000 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8073054 0.87 MAPT (0.44) ALDH1A1MAPTRAB9ANPC1MAPK1
SCHEMBL26840181 0.79 ALDH1A1 (0.59) ALDH1A1MAPTRAB9ANPC1MAPK1
SCHEMBL9741841 0.79 ALDH1A1 (0.59) ALDH1A1MAPTRAB9ANPC1MAPK1
SCHEMBL5179112 0.79 ALDH1A1 (0.70) ALDH1A1MAPTRAB9ANPC1MAPK1
SCHEMBL8970419 0.79 ALDH1A1 (0.59) ALDH1A1MAPTRAB9ANPC1MAPK1
SCHEMBL50129 0.79 ALDH1A1 (0.59) ALDH1A1MAPTRAB9ANPC1MAPK1
SCHEMBL29962290 0.79 ALDH1A1 (0.59) ALDH1A1MAPTRAB9ANPC1MAPK1
SCHEMBL8776970 0.78 ALDH1A1 (0.46) ALDH1A1MAPTRAB9ANPC1MAPK1
SCHEMBL15290159 0.78 ALDH1A1 (0.75) ALDH1A1MAPTRAB9ANPC1MAPK1
Lithium SCHEMBL31026807 0.78 ALDH1A1 (0.57) ALDH1A1MAPTRAB9ANPC1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4435560-A HEAT RESISTANT, GOOD PROCESSABILITY HITACHI, LTD. (JP) 1984-03-06 US claimed
US-6303743-B1 Polyimide for optical communications, method of preparing the same, and method of forming multiple polyimide film using the polyimide SAMSUNG ELECTRONICS CO., LTD. (KR) 2001-10-16 US disclosed
US-6100371-A Polyimide for optical communications and method for preparing the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2000-08-08 US disclosed
US-6077928-A Bis(dialkylmaleimide) derivative and polyetherimide for optical communications formed therefrom SAMSUNG ELECTRONICS CO., LTD. (KR) 2000-06-20 US disclosed
EP-0700532-B1 ALIGNMENT LAYER FOR LIQUID CRYSTALS AVENTIS RES & TECH GMBH & CO (DE) 2000-03-29 EP disclosed
US-6031061-A Bis (triaklyltrimellitic anhydride) derivative and polyesterimide for optical communications formed therefrom SAMSUNG ELECTRONICS CO., LTD. (KR) 2000-02-29 US disclosed
US-6028159-A Polyamideimide for optical communications and method for preparing the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2000-02-22 US disclosed
US-6013759-A Polyamideimide for optical communications and method for preparing the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2000-01-11 US disclosed
US-5744203-A POLYMER MIXTURES OF POLYURETHANES, POLYESTERS, POLYIMIDES, POLYCARBONATES AND POLYUREAS HOECHST AKTIENGESELLSCHAFT (DE) 1998-04-28 US disclosed
EP-0604885-B1 Liquid crystal display device HOECHST AG (DE) 1997-12-10 EP disclosed
US-4904758-A Low-melting polyimide copolymer and method for preparing the same CHISSO CORPORATION (JP) 1990-02-27 US disclosed
EP-0341028-A2 Process for the preparation of photosensitive polymers Chisso Corporation (JP) 1989-11-08 EP disclosed
EP-0336536-A2 Organic-solvent soluble polyimide and production thereof Hitachi Chemical Co., Ltd. (JP) 1989-10-11 EP disclosed
US-4791157-A REACTING TRIMELLITIC ACID WITH AROMATIC DIAMINE WITH ETHER GROUPS HITACHI CHEMICAL CO. (JP) 1988-12-13 US disclosed
EP-0032745-B1 ETHER IMIDES AND PROCESS FOR PRODUCING THE SAME Hitachi, Ltd. (JP) 1987-01-07 EP disclosed
EP-0047530-B1 MALEIMIDE RESIN COMPOSITION AND PROCESS FOR ITS PRODUCTION Hitachi, Ltd. (JP) 1986-12-10 EP disclosed
US-4460783-A AMIDATION, CYCLIZATION, DEHYDRATION HITACHI, LTD. (JP) 1984-07-17 US disclosed
US-4435560-A HEAT RESISTANT, GOOD PROCESSABILITY HITACHI, LTD. (JP) 1984-03-06 US disclosed
EP-0047530-A2 Maleimide resin composition and process for its production Hitachi, Ltd. (JP) 1982-03-17 EP disclosed
EP-0032745-A2 Ether imides and process for producing the same Hitachi, Ltd. (JP) 1981-07-29 EP disclosed