SCHEMBL50129

SCHEMBL50129

Nc1ccc(Oc2ccc(C(c3ccc(Oc4ccc(N)cc4)cc3)(C(F)(F)F)C(F)(F)F)cc2)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.59
MAPT P10636 5/20 0.59
NPC1 O15118 3/20 0.59
RAB9A P51151 3/20 0.59
HPGD P15428 1/20 0.59
MAPK1 P28482 1/20 0.59
TDP1 Q9NUW8 2/20 0.58
CYP3A4 P08684 1/20 0.58
TSHR P16473 1/20 0.58
MAOA P21397 2/20 0.50
MAOB P27338 3/20 0.48
TEAD4 Q15561 1/20 0.48
SMN1; SMN2 Q16637 3/20 0.47
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
POLB P06746 1/20 0.47
MITF O75030 1/20 0.47
GAA P10253 1/20 0.47
GFER P55789 1/20 0.47
NLRP1 Q9C000 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8970419 1.00 ALDH1A1 (0.59) ALDH1A1MAPTNPC1RAB9AHPGD
SCHEMBL9741841 1.00 ALDH1A1 (0.59) ALDH1A1MAPTNPC1RAB9AHPGD
SCHEMBL26840181 1.00 ALDH1A1 (0.59) ALDH1A1MAPTNPC1RAB9AHPGD
SCHEMBL29962290 1.00 ALDH1A1 (0.59) ALDH1A1MAPTNPC1RAB9AHPGD
Hydrochloric Acid SCHEMBL8644359 0.98 ALDH1A1 (0.57) ALDH1A1MAPTNPC1RAB9AHPGD
Lithium SCHEMBL31026807 0.98 ALDH1A1 (0.57) ALDH1A1MAPTNPC1RAB9AHPGD
SCHEMBL6752822 0.94 KIF11 (0.53) ALDH1A1MAPTNPC1RAB9AHPGD
SCHEMBL23643770 0.93 ALDH1A1 (0.52) ALDH1A1MAPTNPC1RAB9AHPGD
SCHEMBL29140665 0.93 MAOA (0.59) ALDH1A1MAPTNPC1RAB9AHPGD
SCHEMBL13883836 0.91 TEAD4 (0.66) ALDH1A1MAPTNPC1RAB9AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 7818 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122078041-A Chemical modification enhancement type screen printing screen 2026-05-26 CN claimed
US-12630739-B2 Polyimide precursor composition and optical multilayer structure formed using the same SK INNOVATION CO., LTD. (KR) 2026-05-19 US claimed
WO-2026101259-A1 METHOD FOR EVALUATING SURFACE RESISTANCE UNIFORMITY OF POLYIMIDE MOLDED PRODUCT, AND POLYIMIDE MOLDED PRODUCT HAVING UNIFORM SURFACE RESISTANCE 피아이첨단소재 주식회사 2026-05-15 WO claimed
US-20260132256-A1 POLYAMIC ACID COMPOSITION AND POLYIMIDE PREPARED WITH THE SAME PI ADVANCED MAT CO LTD (KR) 2026-05-14 US claimed
US-20260132262-A1 BLACK POLYIMIDE FILM AND THE MANUFACTURING METHOD THEREOF PI ADVANCED MAT CO LTD (KR) 2026-05-14 US claimed
CN-122011382-A Composite resin and preparation method and application thereof, gas separation membrane and preparation method and application thereof 中石油(上海)新材料研究院有限公司 2026-05-12 CN claimed
CN-119193064-B Comb type poly (arylene ether nitrile) modified epoxy resin adhesive and preparation method thereof 黑龙江省科学院石油化学研究院 2026-05-12 CN claimed
US-20260125577-A1 SELF-LUBRICATING POLYIMIDE VARNISH AND POLYIMIDE COATING PREPARED THEREFROM PI ADVANCED MAT CO LTD (KR) 2026-05-07 US claimed
US-12619005-B2 Optical film with improved optical properties, display apparatus comprising same, and manufacturing method therefor KOLON INDUSTRIES, INC. (KR) 2026-05-05 US claimed
US-12619010-B2 Optical multilayer structure and method of manufacturing the same SK INNOVATION CO., LTD. (KR) 2026-05-05 US claimed
EP-0299785-A2 Wear resistant solid film lubricants, their preparation and use ETHYL CORPORATION (US) 1989-01-18 EP claimed
EP-0299865-A2 Process for preparing low dielectric polyimides NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) 1989-01-18 EP claimed
EP-0298668-A2 High temperature adhesive for polyimide films and its use ETHYL CORPORATION (US) 1989-01-11 EP claimed
EP-0287355-A2 Polyimide precursors, their use and formation ETHYL CORPORATION (US) 1988-10-19 EP claimed
US-4760126-A Fluorine-containing polyamide-acid derivative and polyimide HITACHI, LTD. (JP) 1988-07-26 US claimed
US-4658010-A Polyimide adhesive and method of making from lactam, dianhydride mixture and diamine LONG JOHN V (US) 1987-04-14 US claimed
EP-0198973-A2 Method of making imide precursor compositions for polimide adhesives and matric materials Long, John V. (US) 1986-10-29 EP claimed
US-4603061-A Process for preparing highly optically transparent/colorless aromatic polyimide film THE UNITED STATES OF AMERICA AS REPRESENTED BY THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) 1986-07-29 US claimed
US-4496711-A CYCLIZATION AT LOW TEMPERATURES THE REACTION PRODUCT ON AN ANHYDRIDE, DIAMINE AND AMINE-CONTAINING ACETYLENE OR NITRILE HUGHES AIRCRAFT COMPANY (US) 1985-01-29 US claimed
US-4485231-A ADDITION POLYMERIZABLE HUGHES AIRCRAFT COMPANY (US) 1984-11-27 US claimed